Rchr
J-GLOBAL ID:201501016996354130   Update date: Feb. 01, 2024

Takeya Motohiro

タケヤ モトヒロ | Takeya Motohiro
Affiliation and department:
Homepage URL  (1): https://kaken.nii.ac.jp/d/r/90155052.ja.html
Research field  (4): Respiratory medicine ,  Experimental pathology ,  Human pathology ,  Metabolism and endocrinology
Research keywords  (30): マクロファージ ,  免疫組織化学 ,  モノクローナル抗体 ,  スカベンジャー受容体 ,  SR-AI, II(CD204) ,  ACAT-1 ,  肉芽腫 ,  CD204 ,  スカベンジャー受容体ファミリー ,  オルタナティブ活性化 ,  ノックアウトマウス ,  LOX-1 ,  CD36 ,  天然化合物 ,  単球 ,  LOX-1(Lectin-like oxidized LDL receptor-1) ,  CD204欠損マウス ,  MCP-1 ,  免疫組織科学 ,  TRPM-3陽性マクロファージ ,  遺伝子欠損マウス ,  樹状細胞 ,  corosolic acid ,  MARCO受容体 ,  泡沫細胞化 ,  マクロファージ活性化 ,  SR-AI,II ,  α1-antitrypsin ,  組織マクロファージ ,  粥状動脈硬化
Research theme for competitive and other funds  (29):
  • 2017 - 2020 Strategic analysis for the development of new anticancer treatments targeting tumor-associated macrophages
  • 2016 - 2019 Search of the new biomarkers reflecting lymph node macrophage function and its application to molecular pathology
  • 2013 - 2016 Does the balance in lymphoma of immunity become the prognostic factor of cancer?
  • 2013 - 2015 Analysis of activation pathways and functional heterogeneity of macrophages - beyond M1/M2 paradigm
  • 2011 - 2013 Development of new therapeutic strategies for regulating macrophage activation by natural compounds
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Papers (268):
  • 菰原 義弘, 竹屋 元裕. 【マクロファージの功罪-疾患病態誘導と制御におけるマクロファージの役割】がん・腫瘍 がん・悪性腫瘍におけるマクロファージ. 医学のあゆみ. 2020. 273. 10. 986-992
  • Yasuhiro Sakai, Andri Rezano, Seiji Okada, Takahiro Ohtsuki, Yoshiaki Kawashima, Tetsuya Tsukamoto, Motoshi Suzuki, Michinori Kohara, Motohiro Takeya, Nobuo Sakaguchi, et al. A Novel Cytological Model of B-Cell/Macrophage Biphenotypic Cell Hodgkin Lymphoma in Ganp-Transgenic Mice. Cancers. 2020. 12. 1
  • Umemoto S, Haruta M, Sakisaka M, Ikeda T, Tsukamoto H, Komohara Y, Takeya M, Nishimura Y, Senju S. Cancer therapy with major histocompatibility complex-deficient and interferon β-producing myeloid cells derived from allogeneic embryonic stem cells. Cancer science. 2019. 110. 10. 3027-3037
  • Yamashita T, Ohnishi K, Ueda M, Masuda T, Inoue Y, Misumi Y, Ueda A, Obayashi K, Takeya M, Ando Y. Transthyretin amyloid-related cerebral angiitis after liver transplantation. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 2019. 26. sup1. 11-12
  • Nana Motojima, Yuta Nakashima, Yukio Fujiwara, Yoshihiro Komohara, Motohiro Takeya, Hiromasa Miura, Kazunori Hino, Hidehiko Higaki, Hidehiro Hata, Yoshitaka Nakanishi. Relationship between wear behaviour of ultra-high-molecular-weight polyethylene and surface profile of Co-Cr-Mo alloy in artificial joint. Biosurface and Biotriology. 2019. 5. 1. 1-7
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MISC (902):
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Patents (1):
Books (1):
  • 生命を支えるマクロファージ
    文光堂 2001 ISBN:4830604409
Education (2):
  • 1977 - 1981 Kumamoto University Kumamoto University
  • 1971 - 1977 Kumamoto University School of Medicine
Professional career (1):
  • 医学博士 (熊本大学)
Work history (12):
  • 2019/04 - 現在 Kumamoto Health Science University President
  • 2015/04 - 2019/03 Kumamoto University
  • 2003/04 - 2018/03 熊本大学大学院(細胞病理学分野) 教授
  • 2011/04 - 2015/03 熊本大学生命科学研究部長・大学院医学教育部長・医学部長
  • 2008/04 - 2011/03 熊本大学医学部副医学部長・医学科長
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