Yamamoto Yukiya

ヤマモトユキヤ | Yamamoto Yukiya

Affiliation and department：
Job title： Professor
Homepage URL (1)： https://www.researchgate.net/profile/Yukiya-Yamamoto

Research field (3)： Molecular biology , Tumor diagnostics and therapeutics , Hematology and oncology

Research keywords (12)： gene mutations , chromosomal translocation , disease models , kinase inhibitors , MPN , signal transduction , AML , transcription factors , tumor supressor , APL , phage library , therapeutic antibody

Research theme for competitive and other funds (3)：

2016 - 2020 Identification and functional analysis of gene aberrations in hematological malignancy with complex chromosomal abnormality using RNA-seq analysis
2011 - 2015 Leukemogenic property of acute promyelocytic leukemia gene, BCOR-RARA
2006 - 2007 急性骨髄性白血病抗原に対する網羅的探索と新規抗体療法開発のための基礎的研究

Papers (44)：

Yukiya Yamamoto, Sachiko Iba, Yoko Inaguma, Akinao Okamoto, Akihiro Abe. ELC52: a novel megakaryocytic leukemia cell line with a CALR type 1 mutation. Leukemia. 2024
Yoichiro Ogama, Yuji Kumagai, Norio Komatsu, Marito Araki, Nami Masubuchi, Hiroko Akiyoshi, Tadashi Matsuura, Hiromi Kirisako, Akiko Kyoya, Fumiko Nomura, et al. Phase 1 Clinical Trial of PPMX-T003, a Novel Human Monoclonal Antibody Specific for Transferrin Receptor 1, to Evaluate Its Safety, Pharmacokinetics, and Pharmacodynamics. Clinical Pharmacology in Drug Development. 2022. 12. 6. 579-587
Xinhui Zhao, Boris Bartholdy, Yukiya Yamamoto, Erica K. Evans, Meritxell Alberich-Jordà, Philipp B. Staber, Touati Benoukraf, Pu Zhang, Junyan Zhang, Bon Q. Trinh, et al. PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development. Communications Biology. 2022. 5. 1
Kentaro Hirade, Shigeru Kusumoto, Akihiro Abe, Hatsune Noritake, Asahi Ito, Masaki Ri, Hirokazu Komatsu, Shinsuke Iida, Yukiya Yamamoto. A novel RARA-SNX15 fusion in PML-RARA-positive acute promyelocytic leukemia with t(11;17;15)(q13;q21.2;q24.1). International Journal of Hematology. 2022. 116. 6. 956-960
Akinao Okamoto, Hidetsugu Fujigaki, Chisako Iriyama, Naoe Goto, Hideyuki Yamamoto, Keichiro Mihara, Yoko Inaguma, Yasuo Miura, Katsuya Furukawa, Yukiya Yamamoto, et al. CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma. Blood Advances. 2022. 6. 11. 3230-3233

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MISC (87)：

平出賢太郎, 山本幸也, 安部明弘, 楠本茂, 河合秋美, 白神一秀, 中村智幸, 大岩加奈, 鈴木智貴, 木下史緒理, et al. 新規融合遺伝子RARA-SNX15を伴った急性前骨髄球性白血病の一例(A novel fusion transcript RARA-SNX15 in an APL case harboring t(11;17;15)(q13;q21.2;q24.1)). 日本血液学会学術集会. 2021. 83回. OS3-3
山本秀行, 入山智沙子, 村手健一郎, 伊庭佐知子, 岡本晃直, 山本幸也, 徳田倍将, 岡部麻子, 島寛太, 安田貴彦, et al. 髄液遊離DNAの遺伝子変異解析が有用であった中枢神経症状で発症したMYD88変異陽性骨原発DLBCLの1例. 日本リンパ網内系学会会誌. 2020. 60. 78-78
水谷有希, 佐藤聖子, 大澤道子, 渡邉文子, 西井智香子, 山本幸也, 勝田逸郎, 富田章裕. 急性巨核芽球性白血病の一例. 日本検査血液学会雑誌. 2020. 21. 学術集会. S147-S147
安部明弘, 山本幸也, 山本幸也, 山本秀行, 岡本晃直, 稲熊容子, 入山智沙子, 徳田倍将, 岡本昌隆, 恵美宣彦, et al. t(6;9;22)(q25;q34;q11.2)を有するBCR-ABL1陽性慢性骨髄性白血病に認められたARID1B-EMID1融合遺伝子. 日本血液学会学術集会抄録(Web). 2020. 82nd
入山智沙子, 村手健一郎, 伊庭佐知子, 岡本晃直, 山本秀行, 徳田倍将, 山本幸也, 岡本昌隆, 渡辺宏久, 冨田章裕. 中枢神経悪性リンパ腫における髄液由来DNAを用いた高感度解析法の確立. 日本血液学会学術集会抄録(Web). 2020. 82nd

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Books (1)：

ビジュアル臨床血液形態学(改訂第4版)
南江堂 2021

Lectures and oral presentations (45)：

Phase I Safety Study of Anti-Transferrin Receptor 1 Antibody (PPMX-T003) in Patients with Polycythemia Vera and Erythrocythemia
(ASH Annual Meeting 2024)
骨髄線維症の新たな治療戦略
(Myelofibrosis Web Seminar 2024)
再生不良性貧血の診断と薬物治療
(ITP・AA診療 webセミナー 2024)
ET診療における実践的アプローチ:リスク別管理と薬剤の使い分け
(東海Hematology seminar 2024)
Diagnosis and treatment of essential thrombocythemia
(ET camp 2022 in December 2022)

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Education (2)：

1998 - 2002 Nagoya University graduate school of medicine
1987 - 1993 Nagoya University School of Medicine

Professional career (1)：

M.D., Ph.D. (Nagoya University)

Work history (9)：

2020/04 - 現在 Chubu University College of Life and Health Sciences, Department of Biomedical Sciences Professor
2020/03 - 現在 Fujita Health University Department of Medicine Visiting associate professor
2020/03 - 現在 Fujita Health University Hospital Hematology & Chemotherapy Visiting Physician
2018/10 - 2020/03 Fujita Health University Hematology Associate Professor
2017/04 - 2018/10 Fujita Health University Hematology Associate Professor

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Committee career (5)：

2020/08 - 現在 Perseus Proteomics Inc. Medical Expert
2017/11 - 現在 MPN-JAPAN Medical Expert
2016/09 - 現在 Japanese Society of Hematology Councilor
2023/06 - 2024/05 Japanese Society of Hematology Curator of Genomic Testing Guidelines
2022/08 - 2024/05 National Cancer Center Japan C-CAT curator

Awards (2)：

2008/11 - Medical Research Fellowship of Takeda Science Foundation
2003/11 - KYO Award of Japanese Leukaemia Research Fund

Association Membership(s) (4)：

American Society of Hematology , THE JAPANESE CANCER ASSOCIATION , THE JAPANESE SOCIETY OF HEMATOLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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