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J-GLOBAL ID：201501020345970280   Update date: Aug. 30, 2025

Shima Ai

シマ アイ | Shima Ai
Affiliation and department：
Tokai University School of Engineering, Department of Bioengineering

About Tokai University School of Engineering, Department of Bioengineering


Job title： Lecturer
Research field  (1)： Cell biology
Research keywords  (4)： 培養肉 ,  三次元培養 ,  組織工学 ,  骨格筋
Research theme for competitive and other funds  (4)：
  • 2023 - 2026 両面培養コラーゲン薄膜を用いた骨格筋組織構築
  • 2023 - 2025 培養肉の作製を目的としたトリ初代筋細胞の食用培養条件の検討
  • 2020 - 2023 スフェロイドを用いた血液脳関門(BBB)モデルの作製
  • 2018 - 2020 筋細胞と腱細胞の3次元共培養法を用いた腱を有する骨格筋組織の構築
Papers (17)：
  • Minghao Nie, Ai Shima, Mikihisa Yamamoto, Shoji Takeuchi. Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications. Trends in Biotechnology. 2025. 43. 8. 1938-1960
  • Ai Shima, Haruka Oda, Shoji Takeuchi. Milk-derived extract for skeletal muscle cell cultivation. Food Bioscience. 2025. 66. 106218-106218
  • Minghao Nie, Ai Shima, Kenta Fukushima, Yuya Morimoto, Shoji Takeuchi. A Cylindrical Molding Method for the Biofabrication of Plane-Shaped Skeletal Muscle Tissue. Micromachines. 2021. 12. 11. 1411-1411
  • Mai Furuhashi, Yuya Morimoto, Ai Shima, Futoshi Nakamura, Hiroshi Ishikawa, Shoji Takeuchi. Formation of contractile 3D bovine muscle tissue for construction of millimetre-thick cultured steak. npj Science of Food. 2021. 5. 1
  • Minghao Nie, Shogo Nagata, Hoshimi Aoyagi, Akane Itou, Ai Shima, Shoji Takeuchi. Cell-laden microfibers fabricated using μl cell-suspension. Biofabrication. 2020. 12. 4. 045021-045021
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Books (5)：
  • 代替プロテインによる食品素材開発 : 植物肉・昆虫食・藻類利用食・培養肉が導く食のイノベーション
    エヌ・ティー・エス 2021 ISBN:9784860437244
  • 14歳からの生物学 : 学校では教えてくれない「ヒト」の科学
    白水社 2020 ISBN:9784560097748
  • 動物学の百科事典
    丸善出版 2018
  • 大人のための科学 高校で教わりたかった生物
    日本評論社 2017
  • 動物細胞培養の手法と細胞死・増殖不良・細胞変異を防止する技術
    技術情報協会 2014
Lectures and oral presentations  (11)：
  • Development of cultivated steak meat
    (第13回培養食料研究会(国際細胞農業カンファレンス) 2024)
  • Muscle tissue construction using hollow fiber bioreactor
    (RIKEN BDR Workshop “Exploring Organoid Design with Microengineering” 2024)
  • Development of cultured steak by tissue engineering
    (TERMIS-AP 2022)
  • Development of cultured steak - Technology for the sustainable food production
    (第10回日仏先端科学シンポジウム 2022)
  • THREE-DIMENSIONAL HUMAN BLOOD-BRAIN BARRIER MODEL FOR LONG-TERM ANALYSIS
    (MicroTAS 2018)
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Education (1)：
  • - 2011 東京大学 大学院総合文化研究科博士課程修了
Professional career (2)：
  • Ph.D. (The University of Tokyo)
  • 博士(学術) (東京大学)
Work history (8)：
  • 2025/04 - 現在 Tokai University School of Engineering, Department of Bioengineering Lecturer
  • 2019/04 - 2025/03 The University of Tokyo The Graduate School of Information Science and Technology
  • 2018/10 - 2019/03 The University of Tokyo Institute of Industrial Science
  • 2016/10 - 2018/09 The University of Tokyo Institute of Industrial Science
  • 2015/08 - 2016/09 Kobe University Graduate School of Medicine
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Association Membership(s) (2)：
日本筋学会 ,  日本再生医療学会
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