Sakasegawa Yuji

サカセガワユウジ | Sakasegawa Yuji

Homepage URL (1)： http://db.tohoku.ac.jp/whois/detail/5363b48b949fd4f1a4a5173d5b382fab.html

Research keywords (5)：プリオン病シャペロン治療法早期診断 , diagnosis , therapeutics , chaperone , prion-disease

Research theme for competitive and other funds (2)：

MISC (156)：

Keiko Nishizawa, Ayumi Oguma, Maki Kawata, Yuji Sakasegawa, Kenta Teruya, Katsumi Doh-ura. Efficacy and Mechanism of a Glycoside Compound Inhibiting Abnormal Prion Protein Formation in Prion-Infected Cells: Implications of Interferon and Phosphodiesterase 4D-Interacting Protein. JOURNAL OF VIROLOGY. 2014. 88. 8. 4083-4099
Keiko Nishizawa, Ayumi Oguma, Maki Kawata, Yuji Sakasegawa, Kenta Teruya, Katsumi Doh-ura. Efficacy and Mechanism of a Glycoside Compound Inhibiting Abnormal Prion Protein Formation in Prion-Infected Cells: Implications of Interferon and Phosphodiesterase 4D-Interacting Protein. JOURNAL OF VIROLOGY. 2014. 88. 8. 4083-4099
倉橋洋史, 逆瀬川裕二, 堂浦克美. マウス神経芽細胞腫細胞由来の Proteinase K 耐性プリオン蛋白質 (PrPres) の検出. 蛋白質科学会アーカイブ. 2014. 7. e074
倉橋洋史, 逆瀬川裕二, 堂浦克美. Detection of Proteinase K - resistant p rion protein (PrPres) in mouse neuroblastoma cells. 蛋白質科学会アーカイブ. 2014. 7. e074
Yuji Sakasegawa, Yusuke Goto, Naomi Hachiya, Kiyotoshi Kaneko, Katsumi Doh-Ura. Dominant negative inhibition by GPI anchor-less recombinant prion proteins is observed in persistently prion infected N2a cells in a culture medium-dependent manner. PRION. 2012. 6. 29-29

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Lectures and oral presentations (90)：

A platinum compound enhances the protease sensitivity of PrPres in cell lysates
(APPS2014 2014)
A platinum compound enhances the protease sensitivity of PrPres in cell lysates
(APPS2014 2014)
Glycerol enhances the PrPres production via a PI3K signaling pathway in prion-infected neuroblastoma cells
(APPS2013 2013)
Cell biology and biochemistry for prion regulation
(第86回日本生化学会大会 2013)
Glycerol enhances the PrPres production via a PI3K signaling pathway in prion-infected neuroblastoma cells
(APPS2013 2013)

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Works (10)：

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Work history (3)：

2005 - - 東北大学大学院医学系研究科助教
2005 - - Graduate School of Medical Science, Graduate school of Tohoku University Assistant professor
Tohoku University Graduate School of Medicine Assistant Professor

Awards (2)：

Association Membership(s) (4)：

日本生化学会 , 日本分子生物学会 , 日本生化学会 , 日本分子生物学会

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