Uehara Ryota

ウエハラリヨウタ | Uehara Ryota

Affiliation and department：
Job title：准教授
Homepage URL (1)： https://altair.sci.hokudai.ac.jp/uehara_lab/

Research field (1)： Cell biology

Research keywords (18)： Ploidy , Ploidy , 多倍体 , 一倍体 , Spindle , Motor proteins , Mitosis , Cytokinesis , Centrosome , 細胞質分裂 , endoplasmic reticulum stress , 微小管 , 自己組織化 , 細胞分裂 , 生細胞観察 , 紡錘体 , 中央紡錘体 , 分子モーター

Research theme for competitive and other funds (9)：

2019 - 2024 Principle of body malfunctioning through local cell division failure
2021 - 2023 中心体複製チェックポイントの人工合成による安定一倍体細胞の樹立
2019 - 2022 染色体倍加に伴う慢性的な中心体異常の発生原理と細胞不均一性への寄与
2019 - 2021 ガン形成を駆動する普遍的レアイベント「倍数性逆転」の発生原理に迫る
2017 - 2019 Molecular mechanism of mitotic spindle adaptation to drastic chromosome number changes

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Papers (26)：

Takahiro Yamamoto, Ryota Uehara. Cell shape instability during cytokinesis in tetraploid HCT116 cells. Biochemical and biophysical research communications. 2023. 678. 39-44
Koya Yoshizawa, Akira Matsura, Masaya Shimada, Sumire Ishida-Ishihara, Fuyu Sato, Takahiro Yamamoto, Kan Yaguchi, Eiji Kawamoto, Taruho Kuroda, Kazuya Matsuo, et al. Tetraploidy-linked sensitization to CENP-E inhibition in human cells. Molecular oncology. 2023
Tomoko Kamasaki, Ryota Uehara, Yasuyuki Fujita. Ultrastructural Characteristics of Finger-Like Membrane Protrusions in Cell Competition. Microscopy (Oxford, England). 2022
Takafumi Kamada, Kohei Otomo, Takashi Murata, Kaito Nakata, Shota Hiruma, Ryota Uehara, Mitsuyasu Hasebe, Tomomi Nemoto. Low-invasive 5D visualization of mitotic progression by two-photon excitation spinning-disk confocal microscopy. Scientific reports. 2022. 12. 1. 809-809
Kosuke Nagata, Ken-Ichi Bajo, Hideyuki Mitomo, Ryosuke Fujita, Ryota Uehara, Kuniharu Ijiro, Hisayoshi Yurimoto. Visualization of DNA replication in single chromosome by stable isotope labeling. Cell structure and function. 2021. 46. 2. 95-101

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MISC (1)：

上原亮太, 釜崎とも子, 依田欣哉, 五島剛太. 動物細胞における中央紡錘体の形成・形態制御機構. 日本細胞生物学会大会要旨集. 2014. 66th

Lectures and oral presentations (9)：

A novel link between ploidy level and centrosome homeostasis in mammalian somatic cells
(Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India 2018)
Molecular mechanism of the contractile ring-the plasma membrane interaction during cytokinesis in human cells
(69th JSCB meeting symposium 2017)
Novel link between ploidy level and centrosome homeostasis in mammalian somatic cells
(Cold Spring Harber Asia Meeting “Cilia and Centrosomes” 2017)
動物細胞における中央紡錘体の形成・形態制御機構
(第66回日本細胞生物学会大会シンポジウム 2014)
細胞生物学的手法と数理モデルを用いた細胞質分裂制御の解析
(第6回定量生物学会年会 2013)

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Education (4)：

2003 - 2008 東京大学大学院総合文化研究科広域科学専攻生命環境科学系
2006 - 2006 米国海洋生物学研究所生理学コース
2001 - 2003 The University of Tokyo College of Arts and Sciences Department of Life and Cognitive Sciences
1999 - 2001 The University of Tokyo College of Arts and Sciences

Professional career (1)：

博士(学術) (東京大学大学院総合文化研究科)

Work history (5)：

2017/11 - 現在 Hokkaido Univ. Faculty of Adv. Life Sci. Associate Prof. (PI)
2017/11 - 現在 Hokkaido University Faculty of Advanced Life Science
2013/12 - 2017/10 Hokkaido University
2013/02 - 2013/12 The University of Tokyo
2008/04 - 2013/01 Nagoya University

Awards (3)：

2013/06 - 第65回日本細胞生物学会年会若手優秀発表賞
2012/08 - 米国実験生物学会年会(FASEB meeting)トラベルアウォード
2010/12 - 名古屋大学GCOEシステム生命科学研究若手顕彰

Association Membership(s) (3)：

米国細胞生物学会 , JAPAN SOCIETY FOR CELL BIOLOGY , 日本分子生物学会

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