Izawa Kazushi

イザワカズシ | Izawa Kazushi

Affiliation and department：

Research field (1)： Immunology

Research keywords (2)： autoinflammatory disease , primary immunodeficiency

Research theme for competitive and other funds (6)：

2022 - 2025 原因不明の炎症性疾患におけるI型IFN応答遺伝の発現解析と新規炎症病態の解明
2019 - 2022 Elucidation of molecular mechanism of TNF receptor-associated periodic syndrome by cell technology and multi-omics analysis
2019 - 2021 Mechanisms of caspase-1-independent cell death induced by NLRP3 and NLRC4 disease-associated variants
2016 - 2019 Detection of Low frequent mosaism in autoinflammatory diseases using molecular barcode method
2014 - 2017 Establishing a platform for molecular analysis and drug innovation of auto-inflammatory disorders

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Papers (99)：

Domnica Luca, Sumin Lee, Keiji Hirota, Yasutaka Okabe, Junji Uehori, Kazushi Izawa, Anna-Lisa Lanz, Verena Schütte, Burcu Sivri, Yuta Tsukamoto, et al. Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity. Science Advances. 2024. 10. 9
Takayuki Miyamoto, Kazushi Izawa, Sho Masui, Atsue Yamazaki, Yuichi Yamasaki, Tadashi Matsubayashi, Mayuka Shiraki, Hidenori Ohnishi, Junko Yasumura, Kawabe Tomohiro, et al. Clinical characteristics of cryopyrin-associated periodic syndrome and long-term real-world efficacy and tolerability of canakinumab in Japan: results of a nationwide survey. Arthritis & rheumatology (Hoboken, N.J.). 2024
Susumu Yamazaki, Kazushi Izawa, Masakazu Matsushita, Akinori Moriichi, Dai Kishida, Hajime Yoshifuji, Ken Yamaji, Ryuta Nishikomori, Masaaki Mori, Takako Miyamae. Promoting awareness of terminology related to unmet medical needs in context of rheumatic diseases in Japan: a systematic review for evaluating unmet medical needs. Rheumatology international. 2023. 43. 11. 2021-2030
Kunihiko Moriya, Tomohiro Nakano, Yoshitaka Honda, Miyuki Tsumura, Masato Ogishi, Motoshi Sonoda, Masahiko Nishitani-Isa, Takashi Uchida, Mohamed Hbibi, Yoko Mizoguchi, et al. Human RELA dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity. The Journal of experimental medicine. 2023. 220. 9
Kosuke Noma, Miyuki Tsumura, Tina Nguyen, Takaki Asano, Fumiaki Sakura, Moe Tamaura, Yusuke Imanaka, Yoko Mizoguchi, Shuhei Karakawa, Seiichi Hayakawa, et al. Isolated chronic mucocutaneous candidiasis due to a novel duplication variant of IL17RC. Research square. 2023

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MISC (244)：

日衛嶋栄太郎, 川島祐介, 仁平寛士, 井澤和司, 児玉浩子, 乾あやの, 東口素子, 滝田順子, 小原収, 八角高裕. ろ紙血プロテオーム解析を用いたWilson病新規スクリーニング法の可能性. 日本先天代謝異常学会雑誌. 2023. 39
西小森隆太, 井澤和司, 石村匡崇, 石村匡崇, 井田弘明, 伊藤秀一, 今井耕輔, 大西秀典, 岡田賢, 小原收, et al. 自己炎症性疾患とその類縁疾患の全国診療体制整備,移行医療体制の構築,診療ガイドライン確立に関する研究診療ガイドライン/フローチャート作成,遺伝子検査の臨床的妥当性,有用性の評価と遺伝子診断に関する研究. 自己炎症性疾患とその類縁疾患の全国診療体制整備、移行医療体制の構築、診療ガイドライン確立に関する研究令和3年度総括・分担研究報告書(Web). 2022
森雅亮, 山路健, 吉藤元, 宮前多佳子, 西小森隆太, 井澤和司, 岸田大, 盛一享徳, 井上祐三朗, 平野亨, et al. 難治性・希少免疫疾患におけるアンメットニーズの把握とその解決に向けた研究 PRO(patient reported outcome)の検討とICT(information and technology)化に関する研究. 難治性・希少免疫疾患におけるアンメットニーズの把握とその解決に向けた研究令和3年度総括・分担研究報告書(Web). 2022
Yuzaburo Inoue, Takeshi Yamamoto, Yoshitaka Honda, Kazushi Izawa, Takahiro Yasumi. Partial Trisomy 9p with Clinical Symptoms Resembling Interferonopathies. JOURNAL OF CLINICAL IMMUNOLOGY. 2021
仁平寛士, 井澤和司, 加藤健太郎, 宮本尚幸, 前田由可子, 伊佐真彦, 本田吉孝, 日衛嶋栄太郎, 長谷川嘉則, 川島祐介, et al. A study of adenosine deaminase 2 deficiency by multi-omics analysis. 日本免疫不全・自己炎症学会総会・学術集会プログラム・抄録集. 2021. 4th

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Professional career (1)：

医学博士 (京都大学)

Association Membership(s) (8)：

International Society of Systemic Auto-Inflammatory Diseases , Paediatric Rheumatology European Society , European Society for Immunodeficiencies , 日本アレルギー学会 , 日本小児アレルギー学会 , 日本小児リウマチ学会 , 日本リウマチ学会 , 日本免疫不全・自己炎症学会

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