Rchr
J-GLOBAL ID:201501057175473405   Update date: May. 16, 2024

Saio Tomohide

サイオ トモヒデ | Saio Tomohide
Affiliation and department:
Job title: Professor
Homepage URL  (1): https://saio-lab.jp
Research field  (2): Molecular biology ,  Structural biochemistry
Research keywords  (6): Protein folding ,  molecular chaperone ,  Protein quality control ,  structure ,  protein ,  NMR
Research theme for competitive and other funds  (21):
  • 2023 - 2028 Molecular dissection of plant specialized metabolism machineries
  • 2023 - 2026 Stratification of Protein Aggregation States based on Pattern Recognition for Screening Factors Controlling Phase Separation
  • 2022 - 2025 Mechanism of chaperone activity modulation through promiscuous recognitions
  • 2021 - 2024 Unraveling the mechanism of kinetic regulation in biomolecular folding
  • 2021 - 2024 Organization of kinetics-driven supramolecular chemistry
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Papers (48):
  • Tomohide Saio, Kotone Ishii, Motonori Matsusaki, Hiroyuki Kumeta, Shingo Kanemura, Masaki Okumura. Client recognition differences between PDI and ERp46 to guide oxidative folding. 2024
  • Honoka Kawamukai, Shumpei Takishita, Kazumi Shimizu, Daisuke Kohda, Koichiro Ishimori, Tomohide Saio. Conformational Distribution of a Multidomain Protein Measured by Single-Pair Small-Angle X-ray Scattering. The Journal of Physical Chemistry Letters. 2024. 15. 3. 744-750
  • Naohiko Iguchi, Noriyoshi Isozumi, Yoshikazu Hattori, Tomohiro Imamura, Masatomo So, Hitoki Nanaura, Takao Kiriyama, Nobuyuki Eura, Minako Yamaoka, Mari Nakanishi, et al. Zinc finger domains bind low-complexity domain polymers. 2023
  • Saori Yoshimura, Ryuki Shimada, Koji Kikuchi, Soichiro Kawagoe, Hironori Abe, Sakie Iisaka, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Naoki Tani, et al. Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions. bioRxiv. 2023
  • Sachiho Taniguchi, Yuji Ono, Yukako Doi, Shogo Taniguchi, Yuta Matsuura, Ayuka Iwasaki, Noriaki Hirata, Ryosuke Fukuda, Keitaro Inoue, Miho Yamaguchi, et al. Identification of α-Tocopherol succinate as an RFFL-substrate interaction inhibitor inducing peripheral CFTR stabilization and apoptosis. Biochemical pharmacology. 2023. 215. 115730-115730
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MISC (64):
  • 中川洋, 井上倫太郎, 小田隆, 小田隆, 矢木(内海)真穂, 斉尾智英, 苙口友隆, 長田裕也, 杉山正明, 佐藤衛, et al. Clarification of hierarchical dynamics in protein. 量子ビームサイエンスフェスタ(Web). 2023. 2022
  • 中川洋, 斎尾智英, 長尾道弘, 長尾道弘, 長尾道弘, 井上倫太郎, 杉山正明, 富永大輝, 川北至信. Analysisi of Hierarchy of Structure and Dynamics of Multidomain Proteins. 量子ビームサイエンスフェスタ(Web). 2022. 2021
  • 中曽根祐介, 中岡育也, 大田帆香, 川越聡一郎, 石森浩一郎, 齋尾智英, 寺嶋正秀. Kinetic analyses of photoinduced protein folding and interaction with molecular chaperone SecB. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
  • 金村進吾, 岡田莉奈, 黒井邦巧, 松崎元紀, 齋尾智英, 山口宏, 伊藤大, 李映昊, 中林孝和, 稲葉謙次, et al. 酸化型ガレクチン1の分子構造基盤. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
  • 中川洋, 井上倫太郎, 小田隆, 小田隆, 矢木(内海)真穂, 斉尾智英, 苙口友隆, 長田裕也, 杉山正明, 佐藤衛, et al. Clarification of hierarchical dynamics in protein. 量子ビームサイエンスフェスタ(Web). 2021. 2020
more...
Books (2):
  • Structural Study of Proteins by Paramagnetic Lanthanide Probe Methods
    Springer 2017
  • NMR Structural Biology Using Paramagnetic Lanthanide Probe
    Springer 2016
Lectures and oral presentations  (54):
  • シャペロンから解き明かすタンパク質フォールディングと集合の制御メカニズム
    (日本学術振興会・産学協力委員会 R022 量子構造生物学委員会 第11回 研究会 2023)
  • 生体分子の弱い相互作用をNMRで可視化する
    (第6回「大学発ベンチャー創出研究会」 2023)
  • Integrative Structural Study on a Multidomain Protein Enzyme Utilizing Paramagnetic Lanthanide Ion
    (2023 Asia-Pacific NMR Symposium 2023)
  • Structural and kinetic views of regulators for protein folding and assembly
    (International Symposium on Protein Folding, Aggregation, Misfolding Disease, and Disease Crosstalk 2023)
  • Visualizing conformational changes of a multidomain protein enzyme using paramagnetic probes
    (International Society of Magnetic Resonance (ISMAR) 2023 conference 2023)
more...
Education (3):
  • 2008 - 2011 Hokkaido University Graduate School of Life Science Ph.D. course
  • 2006 - 2008 Hokkaido University Graduate School of Life Science Master course
  • 2002 - 2006 Hokkaido University Faculty of Pharmaceutical Sciences
Professional career (1):
  • 博士(生命科学) (北海道大学)
Work history (9):
  • 2020/09 - 現在 The University of Tokushima Institute of Advanced Medical Sciences Professor
  • 2023/08 - 2025/03 Tokyo Medical and Dental University Medical Research Institute
  • 2023/04 - 2025/03 東北大学客員教授
  • 2023/04 - 2024/03 京都大学客員教授
  • 2021/08 - 2022/03 Nara Medical University
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Committee career (6):
  • 2018 - 現在 Journal of Korean Magnetic Resonance Society Editorial Board
  • 2024/04 - 2026/03 日本生化学会 評議員
  • 2022/04 - 2026/03 日本核磁気共鳴学会 日本核磁気共鳴学会機関誌編集委員
  • 2021/04 - 2025/03 日本核磁気共鳴学会 評議員
  • 2023/04 - 2024/03 日本蛋白質科学会 執行役員
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Awards (6):
  • 2021/11 - 公益財団法人アステラス病態代謝研究会 最優秀理事長賞
  • 2018/11 - The Chemical Society of Japan Research Incentive Award Structural basis for proteostasis regulated by molecular chaperones
  • 2018/11 - 日本化学会北海道支部 日本化学会北海道支部研究奨励賞 細胞内恒常性維持を担うシャペロンの動的構造基盤と制御
  • 2014/06 - Protein Science Society of Japan Young Scientist Award Structural Basis for Protein Anti-Aggregation Activity of the Trigger Factor Chaperone
  • 2010/08 - International Conference on Magnetic Resonance in Biological Systems (ICMRBS) 24th ICMRBS Student Poster Award PCS-based structure determination of protein-protein complexes
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Association Membership(s) (5):
THE CHEMICAL SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN ,  日本生物物理学会
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