2017 - 2020 Role of tumor suppressor protein p53-inducible phosphatase PPM1D on neutrophil differentiation
2018 - 2019 脂肪滴形成・融合・分解の制御機構解明を目指した 新規蛍光プローブの開発
2017 - 2018 自然免疫細胞分化におけるSer/ThrホスファターゼPPM1Dの機能解明
2008 - 2010 四量体構造-機能相関解析に基づく癌抑制タンパク質p53の機能修復
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Papers (51):
Yanling Peng, Qitong Huang, Danli Liu, Siyuan Kong, Rui Kamada, Keiko Ozato, Yubo Zhang, Jun Zhu. A single-cell genomic strategy for alternative transcript start sites identification. Biotechnology journal. 2024. 19. 3. e2300516
Tatsuya Sakaguchi, Natsumi Nakagawa, Kenta Mine, Jose Isagani B. Janairo, Rui Kamada, James G. Omichinski, Kazuyasu Sakaguchi. Biomineralization through a Symmetry-Controlled Oligomeric Peptide. Biomimetics. 2023. 8. 8. 606-606
Shuya Sakaguchi, Natsumi Nakagawa, Haytham M. Wahba, Junya Wada, Rui Kamada, James G. Omichinski, Kazuyasu Sakaguchi. Highly Similar Tetramerization Domains from the p53 Protein of Different Mammalian Species Possess Varying Biophysical, Functional and Structural Properties. International Journal of Molecular Sciences. 2023. 24. 23
Rui Kamada, Hiromitsu Miyazaki, Jose Isagani Janairo, Yoshiro Chuman, Kazuyasu Sakaguchi. Bilayer Hydrogel Composed of Elastin-Mimetic Polypeptides as a Bio-Actuator with Bidirectional and Reversible Bending Behaviors. Molecules. 2023. 28. 13
Tatsuki Tsuruoka, Emiri Nakayama, Takuya Endo, Shingo Harashima, Rui Kamada, Kazuyasu Sakaguchi, Toshiaki Imagawa. Development of a fluorescence reporter system to quantify transcriptional activity of endogenous p53 in living cells. Journal of cell science. 2023. 136. 12
R. Kamada, N. Nakagawa, J. Wada, K. Sakaguchi. ARGININE METHYLATION OF TETRAMERIZATION DOMAIN DESTABILIZES THE TETRAMERIC STRUCTURE OF TUMOR SUPPRESSOR PROTEIN P53. JOURNAL OF PEPTIDE SCIENCE. 2016. 22. S128-S128
N. Nakagawa, J. Wada, R. Kamada, T. Nomura, T. Imagawa, K. Sakaguchi. EVOLUTION OF THE TETRAMERIZATION DOMAIN IN TUMOR SUPPRESSOR PROTEIN P53. JOURNAL OF PEPTIDE SCIENCE. 2016. 22. S22-S22
Y. Toguchi, M. Kanno, R. Kamada, T. Imagawa, K. Sakaguchi. THE EFFECTS OF P53 TETRAMERIZATION DOMAIN MUTANTS FOUND IN LI-FRAUMENI SYNDROME ON HETERO-OLIGOMER FORMATION AND TRANSCRIPTIONAL ACTIVITY. JOURNAL OF PEPTIDE SCIENCE. 2016. 22. S86-S88
Tetramer Stability and Functional Regulation of Tumor Suppressor Protein p53
Springer 2012
Education (3):
2007 - 2010 Hokkaido University Graduate School of Science Department of Chemistry
2006 - 2007 Hokkaido University Graduate School of Science Department of Chemistry
2002 - 2006 Hokkaido University School of Science Chemistry
Professional career (1):
博士(理学) (北海道大学)
Work history (5):
2020/04 - 現在 Hokkaido University
2014/05 - 2020/03 Hokkaido University Faculty of Science
2012/05 - 2014/04 National Institutes of Health
2011/04 - 2012/04 Kyoto University Graduate School of Engineering
2008/04 - 2011/03 Hokkaido University Graduate School of Science
Committee career (2):
2022/01 - 現在 日本プロテインホスファターゼ研究会 世話人会
2018/01 - 2021/03 日本ペプチド学会 編集委員
Awards (6):
2022/03 - 2021年度 日本化学会 女性化学者奨励賞
2020/12 - 第14回プロテインホスファターゼ国際カンファレンス Young Investigator Award in ICPP2020 (Best Presentation)
2019/03 - 日本生化学会北海道支部 平成31年度若手奨励賞
2016/11 - 日本プロテインホスファターゼ研究会 奨励賞
2011/03 - 北海道大学 大塚賞
2010/11 - 日本ペプチド学会『第46回ペプチド討論会』 Poster Award 『Inhibition of p53 by introducing tetramerization domain peptide fused with polyvalent cationic sequence into cells』
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Association Membership(s) (4):
日本プロテインホスファターゼ研究会
, THE JAPANESE BIOCHEMICAL SOCIETY
, The Japanese Peptide Society
, THE CHEMICAL SOCIETY OF JAPAN