Hayashi Makoto

ハヤシマコト | Hayashi Makoto

Affiliation and department：
Job title： Junior PI
Homepage URL (2)： https://ja.mthayashilab.com/ , https://www.ifom.eu/en/cancer-research/researchers/makoto-hayashi.php

Research field (1)： Molecular biology

Research keywords (4)： Cell Cycle , Cancer , Telomere , Chromosome

Research theme for competitive and other funds (13)：

2023 - 2025 独自レポーター技術を用いた姉妹染色分体融合制御因子の探索
2020 - 2024 Multilateral analysis of the fate of chromosome fusions
2020 - 2022 The fate of a single sister chromatid fusion during epithelial-to-mesenchymal transition
2020 - 2021 Mechanism of mitotic telomere deprotection by topoisomerase 3 enzyme
2018 - 2020 染色体融合によるM期停止機構の4D解析

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Papers (15)：

Yuki Sato, Makoto T Hayashi. Micronucleus is not a potent inducer of the cGAS/STING pathway. Life Science Alliance. 2024
Diana Romero-Zamora*, Samuel Rogers*, Ronnie Ren Jie Low, Andrew B. Robinson, Scott G. Page, Blake J. E. Lane, Noa Lamm, Fuyuki Ishikawa, Makoto T. Hayashi**, Anthony J. Cesare**, et al. A CPC-shelterin-BTR axis regulates mitotic telomere deprotection. 2024
Diana Romero-Zamora, Makoto T. Hayashi. A non-catalytic N-terminus domain of WRN prevents mitotic telomere deprotection. Scientific Reports. 2023. 13. 1
Katsushi Kagaya, Naoto Noma-Takayasu, Io Yamamoto, Sanki Tashiro, Fuyuki Ishikawa, Makoto T Hayashi. Chromosome instability induced by a single defined sister chromatid fusion. Life Science Alliance. 2020. 3. 12. e202000911-e202000911
V. Pragathi Masamsetti, Ronnie Ren Jie Low, Ka Sin Mak, Aisling O’Connor, Chris D. Riffkin, Noa Lamm, Laure Crabbe, Jan Karlseder, David C. S. Huang, Makoto T. Hayashi, et al. Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection. Nature Communications. 2019. 10. 1

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MISC (26)：

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Books (8)：

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Lectures and oral presentations (49)：

染色体融合に起因する微小核はcGAS/STING経路の強い誘導因子ではない
(日本遺伝学会第96回大会 2024)
染色体融合に起因する微小核はcGAS-STING経路の活性化能が低い
(第3回細胞分裂研究会 2024)
染色体融合に起因する微小核はcGAS/STING経路の活性化能が低い
(第76回日本細胞生物学会大会 2024)
Micronucleus Derived from Chromosome Fusion Is Not a Potent Inducer of cGAS-STING Pathway
(EMBO Workshop Telomere function and evolution in health and disease 2024)
The Molecular Mechanism of Mitotic Telomere Deprotection
(The 46th MBSJ 2023 2023)

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Education (3)：

Professional career (1)：

Work history (7)：

2020/04 - 現在 Kyoto University/IFOM IFOM-KU Joint Research Laboratory, Department of State-of-the-art and International Medicine, Graduate School of Medicine IFOM Junior PI/ Kyoto University Visiting Associate Professor
2015/04 - 2020/03 Kyoto University
2014/05 - 2015/03 The Salk Institute for Biological Studies MCBL-J Research Associate
2013/05 - 2014/04 The Salk Institute for Biological Studies MCBL-J Research Associate
2011/05 - 2013/04 The Salk Institute for Biological Studies MCBL-J Research Associate

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Committee career (4)：

2024/04 - 現在 L-INSIGHT program, Kyoto University Promotion Committee Members
2021/04 - 2024/03 JST Training Advisor, Comprehensive Support Project for the Strategic Professional Development Program for Young Researchers
2020/01 - 2020/12 第43回日本分子生物学会年会プログラム委員
2017/01 - 2017/12 第40回日本分子生物学会年会・第90回日本生化学会大会プログラム委員

Awards (2)：

Association Membership(s) (3)：

THE JAPANESE CANCER ASSOCIATION , JAPAN SOCIETY FOR CELL BIOLOGY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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