Hayashi Makoto

ハヤシマコト | Hayashi Makoto

Affiliation and department：
Job title： Junior PI
Homepage URL (2)： https://ja.mthayashilab.com/ , https://www.ifom.eu/en/cancer-research/researchers/makoto-hayashi.php

Research field (1)： Molecular biology

Research keywords (4)： Cell Cycle , Cancer , Telomere , Chromosome

Research theme for competitive and other funds (19)：

2025 - 2030 細胞周期依存性抗がん剤の薬理効果に資するM期テロメア脱保護の分子機構の解明
2025 - 2028 Mechanisms and physiological functions of mitotic telomere deprotection
2023 - 2028 細胞周期依存性抗がん剤の薬理効果に資するM期テロメア脱保護の分子機構の解明
2025 - 2026 WRNを介したM期テロメア脱保護制御機構の解明
2024 - 2025 WRNを介したM期テロメア脱保護制御機構の解明

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Papers (16)：

Diana Romero-Zamora, Samuel Rogers, Ronnie Ren Jie Low, Scott G Page, Blake J E Lane, Shunya Kosaka, Andrew B Robinson, Lucy French, Noa Lamm, Fuyuki Ishikawa, et al. A CPC-shelterin-BTR axis regulates mitotic telomere deprotection. Nature communications. 2025. 16. 1. 2277-2277
Yuki Sato, Makoto T Hayashi. Micronucleus is not a potent inducer of the cGAS/STING pathway. Life Science Alliance. 2024
Diana Romero-Zamora, Makoto T. Hayashi. A non-catalytic N-terminus domain of WRN prevents mitotic telomere deprotection. Scientific Reports. 2023. 13. 1
Makoto T Hayashi. The Mechanism of Mitotic Telomere Deprotection. Cancer Science. 2022
Katsushi Kagaya, Naoto Noma-Takayasu, Io Yamamoto, Sanki Tashiro, Fuyuki Ishikawa, Makoto T Hayashi. Chromosome instability induced by a single defined sister chromatid fusion. Life Science Alliance. 2020. 3. 12. e202000911-e202000911

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MISC (26)：

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Books (9)：

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Lectures and oral presentations (57)：

Regulation of Mitotic Telomere Deprotection by RECQ helicases
(2025)
The Molecular Mechanism of Mitotic Telomere Deprotection
(CSI Singapore Research Seminar 2025)
The Mechanism of Mitotic Arrest-Dependent Telomere Deprotection
(RIKEN Seminar 2025 July 28 2025)
上皮間葉転換における染色体融合の運命解析
(第4回細胞分裂研究会 2025)
Development of L1 Retrotransposon and eccDNA Reporters for Probing cGAS-STING-Mediated Innate Immune Responses
(Joint Meeting of 77th JSCB and 58th JSDB 2025)

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Education (3)：

Professional career (1)：

Work history (7)：

2020/04 - 現在 Kyoto University/IFOM IFOM-KU Joint Research Laboratory, Department of State-of-the-art and International Medicine, Graduate School of Medicine IFOM Junior PI/ Kyoto University Visiting Associate Professor
2015/04 - 2020/03 Kyoto University
2014/05 - 2015/03 The Salk Institute for Biological Studies MCBL-J Research Associate
2013/05 - 2014/04 The Salk Institute for Biological Studies MCBL-J Research Associate
2011/05 - 2013/04 The Salk Institute for Biological Studies MCBL-J Research Associate

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Committee career (4)：

2024/04 - 現在 L-INSIGHT program, Kyoto University Promotion Committee Members
2021/04 - 2024/03 JST Training Advisor, Comprehensive Support Project for the Strategic Professional Development Program for Young Researchers
2020/01 - 2020/12 第43回日本分子生物学会年会プログラム委員
2017/01 - 2017/12 第40回日本分子生物学会年会・第90回日本生化学会大会プログラム委員

Awards (2)：

Association Membership(s) (3)：

THE JAPANESE CANCER ASSOCIATION , JAPAN SOCIETY FOR CELL BIOLOGY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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