Rchr
J-GLOBAL ID：201501088031762936
Update date: Feb. 15, 2024
Kajikawa Mizuho
カジカワ ミズホ | Kajikawa Mizuho
Affiliation and department：
Homepage URL (1)：
https://www.shoyaku.ac.jp/research/laboratory/kanmen/top
Research field (3)：
Structural biochemistry
, Functional biochemistry
, Virology
Research keywords (14)：
Nox
, NADPHオキシダーゼ
, MHC様分子
, MILL
, MHCクラスIb
, 非古典的MHCクラスI
, 主要組織適合遺伝子複合体
, KSHV
, MHC
, 免疫受容体
, ユビキチンリガーゼ
, ウイルス
, 膜タンパク質
, 免疫回避
Research theme for competitive and other funds (5)：
- 2022 - 2025 新規リガンド同定によるKSHV細胞増殖活性化分子K1の新たな機能解明
- 2019 - 2022 Identification of a novel immune evasion strategy of KSHV based on substrate specificity of ubiquitin ligase
- 2015 - 2018 Substrate recognition mechanism of KSHV immune evasion molecule MIR
- 2013 - 2015 The novel substrate recognition mechanism of KSHV MIR family
- 2010 - 2011 The molecular basis of substrate recognition by KSHV MIR
Papers (37)：
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Mizuho Kajikawa, Koya Kato, Hayato Takahashi, Seiya Kitajima, Yosuke Kusunoki, Mizuki Haga, Minako Kimura, Yoshihiro Inoue, Kei Miyano, Taisei Kanamoto. A basic charge cluster near the C-terminus of the cytoplasmic tail contributes to the molecular stability of human herpesvirus 8 E3 ubiquitin ligases. Microbiology and immunology. 2023. 67. 6. 293-302
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Chikage Kawai, Mizuho Kajikawa, Akira Yamauchi, Shuichiro Okamoto, Futoshi Kuribayashi, Kei Miyano. Characterization of missense mutations in the NADPH oxidase partner p22phox in the A22° subtype of chronic granulomatous disease. Microbiology and immunology. 2023. 67. 4. 194-200
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Kei Miyano, Mizuho Kajikawa. Ca2+ -binding-region-dependent cell surface localization of NADPH oxidase Nox5. FEBS letters. 2023. 597. 5. 702-713
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Mizuho Kajikawa, Mizuki Hata, Maho Ishimura, Nanae Imaizumi, Minako Kimura, Kei Miyano, Toyoyuki Ose, Daisuke Asai, Satoshi Ishido, Taisei Kanamoto. Importance of accessibility to the extracellular juxtamembrane stalk region of membrane protein for substrate recognition by viral ubiquitin ligase K5. The Biochemical journal. 2022. 479. 20. 2261-2278
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Kei Miyano, Shuichiro Okamoto, Mizuho Kajikawa, Takuya Kiyohara, Chikage Kawai, Akira Yamauchi, Futoshi Kuribayashi. Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22 by thiol modification. Redox biology. 2022. 56. 102479-102479
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MISC (56)：
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宮野佳, 梶川瑞穂. Protein stabilization mechanisms of reactive oxygen species-producing NADPH oxidase. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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宮野佳, 岡本秀一郎, 梶川瑞穂, 清原卓也, 川井千景, 山内明, 栗林太. 活性酸素生成酵素NADPHオキシダーゼのパートナー分子p22phoxの分解制御機構の解明. 日本酸化ストレス学会学術集会プログラム・抄録集. 2023. 76th
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川井千景, 岡本秀一郎, 梶川瑞穂, 山内明, 栗林太, 宮野佳. The epitopes in human gp91phox/Nox2 recognized by mAbs CL-5 and 48. 日本生体防御学会学術総会講演抄録集. 2022. 33rd
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宮野佳, 岡本秀一郎, 山内明, 梶川瑞穂, 川井千景, 栗林太. 活性酸素生成酵素Nox4による内皮細胞遊走の促進機構の解明. 日本生化学会大会(Web). 2021. 94th
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宮野佳, 岡本秀一郎, 山内明, 梶川瑞穂, 川井千景, 栗林太. ROS-generating Nox4 promotes the directed migration of endothelial cells. 日本生体防御学会学術総会講演抄録集. 2021. 32nd
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Patents (1)：
Books (4)：
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薬系免疫学(改訂第4版)
南江堂 2022 ISBN:9784524404117
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薬系免疫学(改訂第3版)
南江堂 2018 ISBN:4524403515
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薬系免疫学(改訂第2版)
南江堂 2012 ISBN:4524402969
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薬系免疫学
南江堂 2007 ISBN:4524402462
Education (3)：
- 2003 - 2006 The Graduate University for Advanced Studies School of Advanced Sciences Department of Biosystems Science
- 2001 - 2003 Shizuoka University Graduate School of Science and Engineering
- 1997 - 2001 Shizuoka University Faculty of Science
Professional career (1)：
Work history (4)：
- 2016/04 - 現在 Showa Pharmaceutical University Faculty of Pharmaceutical Sciences
- 2012/10 - 2016/03 Showa Pharmaceutical University Faculty of Pharmaceutical Sciences
- 2009/04 - 2012/09 RIKEN
- 2006/10 - 2009/03 Kyushu University Medical Institute of Bioregulation
Association Membership(s) (3)：
Japanese society for host defense research
, THE JAPANESE SOCIETY FOR VIROLOGY
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
