Art

J-GLOBAL ID：201502200715728736   Reference number：15A1311254

Equine herpesvirus type 1 tegument protein VP22 is not essential for pathogenicity in a hamster model, but is required for efficient viral growth in cultured cells

ウマヘルペスウイルス1型テグメント蛋白質VP22はハムスターモデルでの病原性にとって必須ではないが培養細胞における効率的なウイルス培養には必要である

Author (6)： OKADA Ayaka (Dep. of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu Univ., 1-1 Yanagido, Gifu ...) ,  IZUME Satoko (Dep. of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu Univ., 1-1 Yanagido, Gifu ...) ,  OHYA Kenji (Dep. of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu Univ., 1-1 Yanagido, Gifu ...) ,  OHYA Kenji (Lab. of Veterinary Microbiology, Fac. of Applied Biological Sciences, Gifu Univ., 1-1 Yanagido, Gifu 501-1193, JPN) ,  FUKUSHI Hideto (Dep. of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu Univ., 1-1 Yanagido, Gifu ...) ,  FUKUSHI Hideto (Lab. of Veterinary Microbiology, Fac. of Applied Biological Sciences, Gifu Univ., 1-1 Yanagido, Gifu 501-1193, JPN)
Material： Journal of Veterinary Medical Science  (日本獣医学会会誌)
Volume： 77  Issue： 10  Page： 1293-1297 (J-STAGE)  Publication year： 2015 
JST Material Number： F0905A  ISSN： 0916-7250  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *herpes simplex virus 1 ,...
Semi thesaurus term： Alphaherpesvirinae ,...

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JST classification (2)： Microorganism inoculation and culture methods  (EG02030R) ,  Biological function  (EB03040U)

Reference (17)：

• 1. Barnett, B. C., Dolan, A., Telford, E. A., Davison, A. J. and McGeoch, D. J. 1992. A novel herpes simplex virus gene (UL49A) encodes a putative membrane protein with counterparts in other herpesviruses. J. Gen. Virol. 73: 2167-2171.
• 2. Che, X., Reichelt, M., Sommer, M. H., Rajamani, J., Zerboni, L. and Arvin, A. M. 2008. Functions of the ORF9-to-ORF12 gene cluster in varicella-zoster virus replication and in the pathogenesis of skin infection. J. Virol. 82: 5825-5834.
• 3. Dorange, F., Tischer, B. K., Vautherot, J. F. and Osterrieder, N. 2002. Characterization of Marek’s disease virus serotype 1 (MDV-1) deletion mutants that lack UL46 to UL49 genes: MDV-1 UL49, encoding VP22, is indispensable for virus growth. J. Virol. 76: 1959-1970.
• 4. Duffy, C., Lavail, J. H., Tauscher, A. N., Wills, E. G., Blaho, J. A. and Baines, J. D. 2006. Characterization of a UL49-null mutant: VP22 of herpes simplex virus type 1 facilitates viral spread in cultured cells and the mouse cornea. J. Virol. 80: 8664-8675.
• 5. Elliott, G. D. and Meredith, D. M. 1992. The herpes simplex virus type 1 tegument protein VP22 is encoded by gene UL49. J. Gen. Virol. 73: 723-726.

Terms in the title (7)： ウマヘルペスウイルス1 ,  テグメント蛋白質 ,  ハムスター ,  モデル ,  病原性 ,  培養細胞 ,  ウイルス培養