Art

J-GLOBAL ID：201502200879302047   Reference number：15A1289418

Inhibitory Effect of Oleic Acid on Octanoylated Ghrelin Production

オクタノイル化グレリン産生に関するオレイン酸の抑制効果

Author (12)： OISO Shigeru (Graduate School of Pharmaceutical Sciences, Nagasaki International Univ.) ,  OISO Shigeru (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.) ,  NOBE Miyuki (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.) ,  IWASAKI Syuhei (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.) ,  NII Wakana (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.) ,  GOTO Natsumi (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.) ,  SEKI Yukari (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.) ,  NAKAJIMA Kensuke (Graduate School of Pharmaceutical Sciences, Nagasaki International Univ.) ,  NAKAJIMA Kensuke (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.) ,  NAKAMURA Kazuo (Dep. of Biopharmaceutics, Nihon Pharmaceutical Univ.) ,  KARIYAZONO Hiroko (Graduate School of Pharmaceutical Sciences, Nagasaki International Univ.) ,  KARIYAZONO Hiroko (Dep. of Pharmacy, Fac. of Pharmaceutical Sciences, Nagasaki International Univ.)
Material： Journal of Oleo Science  (J Oleo Sci)
Volume： 64  Issue： 11  Page： 1185-1192 (J-STAGE)  Publication year： 2015 
JST Material Number： G0238A  ISSN： 1345-8957  CODEN： JOSOAP  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Ghrelin ,...
Semi thesaurus term： GHRL8細胞 ,...

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JST classification (1)： Biological function  (EB05020M)

Substance index (6)： Linolenic acid ,  Octanoic acid ,  Oleic Acid ,  Stearic acid ,  Linolic acid ,  Acetic acid

Reference (37)：

• 1) Kojima, M.; Hosoda, H.; Date, Y.; Nakazato, M.; Matsuo, H.; Kangawa, K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660 (1999).
• 2) Nakazato, M.; Murakami, N.; Date, Y.; Kojima, M.; Matsuo, H.; Kangawa, K.; Matsukura, S. A role for ghrelin in the central regulation of feeding. Nature 409, 194-198 (2001).
• 3) Shintani, M.; Ogawa, Y.; Ebihara, K.; Aizawa-Abe, M.; Miyanaga, F.; Takaya, K.; Hayashi, T.; Inoue, G.; Hosoda, K.; Kojima, M.; Kangawa, K.; Nakao, K. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway. Diabetes 50, 227-232 (2001).
• 4) Tschop, M.; Smiley, D. L.; Heiman, M. L. Ghrelin induces adiposity in rodents. Nature 407, 908-913 (2000).
• 5) Wren, A. M.; Small, C. J.; Abbott, C. R.; Dhillo, W. S.; Seal, L. J.; Cohen, M. A.; Batterham, R. L.; Taheri, S.; Stanley, S. A.; Ghatei, M. A.; Bloom, S. R. Ghrelin causes hyperphagia and obesity in rats. Diabetes 50, 2540-2547 (2001).

Terms in the title (3)： グレリン ,  オレイン酸 ,  抑制効果