Art

J-GLOBAL ID：201502203082011062   Reference number：15A1167723

Regorafenib-associated hand-foot skin reaction: practical advice on diagnosis, prevention, and management

レゴラフェニブ関連手足皮膚反応 診断と予防と管理の実践的アドバイス

Author (5)： MCLELLAN B. (Albert Einstein Coll. of Medicine and Jacobi Medical Center, Bronx, USA) ,  CIARDIELLO F. (Seconda Universita degli Studi di Napoli, Napoli, ITA) ,  LACOUTURE M. E. (Memorial Sloan Kettering Cancer Center, New York, USA) ,  SEGAERT S. (KU Leuven, Leuven, BEL) ,  VAN CUTSEM E. (KU Leuven, Leuven, BEL)
Material： Annals of Oncology  (Ann Oncol)
Volume： 26  Issue： 10  Page： 2017-2026  Publication year： Oct. 2015 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： マルチキナーゼ阻害剤 ,...

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JST classification (3)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Skin diseases  (GF03000Q) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Substance index (1)： Regorafenib

Reference (84)：

• Wilhelm SM, Dumas J, Adnane L et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer 2011; 129:245-255.
• Schmieder R, Hoffmann J, Becker M et al. Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer. Int J Cancer 2014; 135: 1487-1496.
• Mross K, Frost A, Steinbild S et al. A phase I dose-escalation study of regorafenib (BAY 73-4506), an inhibitor of oncogenic, angiogenic, and stromal kinases, in patients with advanced solid tumors. Clin Cancer Res 2012; 18: 2658-2667.
• Strumberg D, Scheulen ME, Schultheis B et al. Regorafenib (BAY 73-4506) in advanced colorectal cancer: a phase I study. Br J Cancer 2012; 106:1722-1727.
• Sunakawa Y, Furuse J, Okusaka T et al. Regorafenib in Japanese patients with solid tumors: phase I study of safety, efficacy, and pharmacokinetics. Invest New Drugs 2014; 32: 104-112.

Terms in the title (5)： レゴラフェニブ ,  手足皮膚反応 ,  診断 ,  予防 ,  アドバイス