Art

J-GLOBAL ID：201502203731258357   Reference number：15A0310888

Multigene Knockout Utilizing Off-Target Mutations of the CRISPR/Cas9 System in Rice

イネにおけるCRISPR/Cas9システムのオフ-ターゲット突然変異を利用した多重遺伝子ノックアウト

Author (5)： ENDO Masaki (National Inst. of Agrobiological Sci., Ibaraki, JPN) ,  MIKAMI Masafumi (National Inst. of Agrobiological Sci., Ibaraki, JPN) ,  MIKAMI Masafumi (Yokohama City Univ., Kanagawa, JPN) ,  TOKI Seiichi (National Inst. of Agrobiological Sci., Ibaraki, JPN) ,  TOKI Seiichi (Yokohama City Univ., Kanagawa, JPN)
Material： Plant and Cell Physiology  (Plant & Cell Physiology)
Volume： 56  Issue： 1  Page： 41-47  Publication year： Jan. 2015 
JST Material Number： W1897A  ISSN： 0032-0781  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： cyclin-dependent kinase ,...
Semi thesaurus term： mismatched base pair ,...

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JST classification (2)： Plant biochemistry  (EH01050J) ,  Molecular genetics in general  (EC02010J)

Reference (32)：

• Belhaj, K., Chaparro-Garcia, A., Kamoun, S. and Nekrasov, V. (2013) Plant genome editing made easy: targeted mutagenesis in model and crop plants using the CRISPR/Cas system. Plant Methods 9: 39.
• Cho, S.W., Kim, S., Kim, J.M. and Kim, J.S. (2013) Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31: 230-232.
• Colasanti, J., Tyers, M. and Sundaresan, V. (1991) Isolation and characterization of cDNA clones encoding a functional p34cdc2 homologue from Zea mays. Proc. Natl Acad. Sci. USA 88: 3377-3381.
• Cong, L, Ran, F.A., Cox, D., Lin, S., Barretto, R., Habib, N. et al. (2013) Multiplex genome engineering using CRISPR/Cas systems. Science 339: 819-823.
• Endo, M., Nakayama, S., Umeda-Hara, C., Ohtsuki, N., Saika, H., Umeda, M. et al. (2012) CDKB2 is involved in mitosis and DNA damage response in rice. Plant J. 69: 967-977.

Terms in the title (6)： イネ ,  CRISPR ,  Cas9 ,  ターゲット ,  突然変異 ,  ノックアウト