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J-GLOBAL ID:201502203986537692   Reference number:15A0871452

A Case of Lung Adenocarcinoma with an EGFR-activating Mutation That Transformed to Small-cell Lung Cancer

小細胞癌への転化をきたしたEGFR遺伝子変異陽性肺腺癌の1例
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Volume: 55  Issue:Page: 155-160 (J-STAGE)  Publication year: 2015 
JST Material Number: U0408A  ISSN: 1348-9992  Document type: Article
Article type: 原著論文  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Tumors(=neoplasms)of respiratory system 
Reference (11):
  • 1. Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, et al. Genotype and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med. 2011; 3: 75ra26.
  • 2. Ohashi K, Maruvka YE, Michor F, Pao W. Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease. J Clin Oncol. 2013; 31: 1070-1080.
  • 3. Watanabe S, Sone T, Matsui T, Yamamura K, Tani M, Okazaki A, et al. Transformation to small-cell lung cancer following treatment with EGFR tyrosine kinase inhibitors in a patient with lung adenocarcinoma. Lung Cancer. 2013; 82: 370-372.
  • 4. Nguyen KS, Kobayashi S, Costa DB. Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. Clin Lung Cancer. 2009; 10: 281-289.
  • 5. Fukui T, Tsuta K, Furuta K, Watanabe S, Asamura H, Ohe Y, et al. Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung. Cancer Sci. 2007; 98: 1714-1719.
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