Art

J-GLOBAL ID：201502206901100567   Reference number：15A0925882

2D/3D-QSAR Studies of [1,2,4]Triazolo[1,5-a]pridinylpyridine Derivatives as Potent Anticancer Agents

強力な抗腫よう薬としての[1,2,4]トリアゾロ[1,5-a]プリジニルピリジン誘導体の二次元/三次元QSAR研究【Powered by NICT】

Author (6)： Chen Jincan (School of Pharmacy, Guangdong Medical Coll., Zhanjiang) ,  Li Guodong (School of Pharmacy, Guangdong Medical Coll., Zhanjiang) ,  Qian Li (Youjiang Medical Coll. for Nationalities) ,  Chen Lanmei (School of Pharmacy, Guangdong Medical Coll., Zhanjiang) ,  Xu Bilian (School of Pharmacy, Guangdong Medical Coll., Zhanjiang) ,  Zheng Kangcheng (School of Chemistry and Chemical Engineering, Sun Yat-Sen Univ., Guangzhou)
Material： Chinese Journal of Structural Chemistry  (Jiegou Huaxue)
Volume： 33  Issue： 12  Page： 1729-1740  Publication year： 2014 
JST Material Number： C2524A  ISSN： 0254-5861  CODEN： JHUADF  Document type： Article
Article type： 原著論文  Country of issue： China (CHN)  Language： ENGLISH (EN)

Abstract/Point： By using a combined method of ...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=15A0925882&from=J-GLOBAL&jstjournalNo=C2524A") }}

Thesaurus term： *antitumor drug ,  hydrogen bond ,  intramolecular dynamics ,  hydrophobic ,  antitumor action ,  density functional method ,  *quantitative structure-activity relationship ,  hydrophilicity ,  action mechanism ,  donor
Semi thesaurus term： 予測能力 ,  PI3K阻害剤 ,  腫瘍細胞株 ,  CoMSIA ,  CoMFA , 【Automatic Indexing@JST】

JST classification (2)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Structure-activity relationship of drugs  (GV01050B)

Terms in the title (4)： 抗腫よう薬 ,  誘導体 ,  三次元QSAR ,  研究