Art

J-GLOBAL ID：201502208887006504   Reference number：15A1033075

First Total Synthesis of Neoantimycin

ネオアンチマイシンの初めての全合成

Author (3)： OGAWA Hikaru (Div. of Molecular Materials Sci., Graduate School of Sci., Osaka City Univ.) ,  IIO Hideo (Div. of Molecular Materials Sci., Graduate School of Sci., Osaka City Univ.) ,  USUKI Yoshinosuke (Div. of Molecular Materials Sci., Graduate School of Sci., Osaka City Univ.)
Material： Chemistry Letters  (Chem Lett)
Volume： 44  Issue： 9  Page： 1214-1216 (J-STAGE)  Publication year： 2015 
JST Material Number： S0742A  ISSN： 0366-7022  CODEN： CMLTAG  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *total synthesis ,  analysis ,  *ring enlargement reaction ,  *antibiotics ,  condensation reaction ,  cyclization reaction ,  computer simulation ,  molecular structure ,  oxygen heterocyclic compound ,  phenolic compound ,  carboxamide
Semi thesaurus term： ring extension ,  retrosynthetic analysis ,  molecular dynamics calculation ,  ring closure reaction

JST classification (2)： Eight or more-membered heterocyclic compounds  (CF07120T) ,  Other natural substances of biological origin  (CF10090R)

Substance index (1)： N-[(3S,6S,7R,10S,14R,15R)-15-Benzyl-10-sec-butyl-14-hydroxy-3-isopropyl-7,13,13-trimethyl-2,5,9,12-tetraoxo-1,4,8,11-tetraoxacyclopentadecane-6-yl]-3-(formylamino)-2-hydroxybenzamide

Reference (19)：

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• 3) Y. Takeda, T. Masuda, T. Matsumoto, Y. Takechi, T. Shingu, H. G. Floss, J. Nat. Prod. 1998, 61, 978.
• 4) a) Y. Umeda, S. Chijiwa, K. Furihata, K. Furihata, S. Sakuda, H. Nagasawa, H. Watanabe, K. Shin-ya, J. Antibiot. 2005, 58, 206.
•  b) Y. Umeda, K. Furihata, S. Sakuda, H. Nagasawa, K. Ishigami, H. Watanabe, M. Izumikawa, M. Takagi, T. Doi, Y. Nakao, K. Shin-ya, Org. Lett. 2007, 9, 4239.

Terms in the title (1)： 全合成