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J-GLOBAL ID：201502209900696171   Reference number：15A1169653

MT1-MMP recognition by ERM proteins and its implication in CD44 shedding

ERM蛋白質によるMT1-MMPの認識とCD44分解におけるその意義

Author (5)： TERAWAKI Shin-ichi (Structural Biology Lab., Nara Inst. of Sci. and Technol., 8916-5 Takayama, Ikoma, Nara, 630-0192, JPN) ,  KITANO Ken (Structural Biology Lab., Nara Inst. of Sci. and Technol., 8916-5 Takayama, Ikoma, Nara, 630-0192, JPN) ,  AOYAMA Miki (Structural Biology Lab., Nara Inst. of Sci. and Technol., 8916-5 Takayama, Ikoma, Nara, 630-0192, JPN) ,  MORI Tomoyuki (Structural Biology Lab., Nara Inst. of Sci. and Technol., 8916-5 Takayama, Ikoma, Nara, 630-0192, JPN) ,  HAKOSHIMA Toshio (Structural Biology Lab., Nara Inst. of Sci. and Technol., 8916-5 Takayama, Ikoma, Nara, 630-0192, JPN)
Material： Genes to Cells  (Genes Cells)
Volume： 20  Issue： 10  Page： 847-859  Publication year： Oct. 2015 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *actin binding protein ,...
Semi thesaurus term： *シェダーゼ ,...

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JST classification (2)： Biological function  (EB03040U) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (58)：

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• Artym, V.V., Zhang, Y., Seillier-Moiseiwitsch, F., Yamada, K.M. & Mueller, S.C. (2006) Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. Cancer Res. 66, 3034-3043.
• Bajorath, J. (2000) Molecular organization, structural features, and ligand binding characteristics of CD44, a highly variable cell surface glycoprotein with multiple functions. Proteins 39, 103-111.
• Bretscher, A., Edwards, K. & Fehon, R.G. (2002) ERM proteins and merlin: integrators at the cell cortex. Nat. Rev. Mol. Cell Biol. 3, 586-599.

Terms in the title (4)： ERM蛋白質 ,  MT1-MMP ,  CD44 ,  分解