Art

J-GLOBAL ID：201502211787876994   Reference number：15A0733331

Characterization of Russell Bodies Accumulating Mutant Antithrombin Derived from the Endoplasmic Reticulum

小胞体に由来する変異体アンチトロンビンを蓄積するラッセル小体の特性解析

Author (7)： KIMURA Koji (Dep. of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, Univ. of Toyama) ,  KAWAGUCHI Kosuke (Dep. of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, Univ. of Toyama) ,  UEDA Yumiko (Dep. of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, Univ. of Toyama) ,  ARAI Seisuke (Dep. of Cell Sci., Inst. of Biomedical Sciences, Fukushima Medical Univ. School of Medicine) ,  MORITA Masashi (Dep. of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, Univ. of Toyama) ,  IMANAKA Tsuneo (Dep. of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, Univ. of Toyama) ,  WADA Ikuo (Dep. of Cell Sci., Inst. of Biomedical Sciences, Fukushima Medical Univ. School of Medicine)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 38  Issue： 6  Page： 852-861 (J-STAGE)  Publication year： 2015 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antithrombin ,...
Semi thesaurus term： *ラッセル小体 ,...

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JST classification (2)： Proteins and peptides in general  (EB03010N) ,  Cell components in general  (EF03010Z)

Reference (36)：

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• 3) Kikkert M, Doolman R, Dai M, Avner R, Hassink G, van Voorden S, Thanedar S, Roitelman J, Chau V, Wiertz E. Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum. J. Biol. Chem., 279, 3525-3534 (2004).
• 4) Claessen JH, Kundrat L, Ploegh HL. Protein quality control in the ER: balancing the ubiquitin checkbook. Trends Cell Biol., 22, 22-32 (2012).
• 5) Scheper W, Hoozemans JJ. Endoplasmic reticulum protein quality control in neurodegenerative disease: the good, the bad and the therapy. Curr. Med. Chem., 16, 615-626 (2009).

Terms in the title (5)： 小胞体 ,  変異体 ,  アンチトロンビン ,  蓄積 ,  特性解析