Art

J-GLOBAL ID：201502212237196690   Reference number：15A0335014

Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes

ムコリピン1はリソソームへのRNA輸送を促進することにより樹状細胞におけるTLR7応答を確実に制御する

Author (6)： LI Xiaobing (Univ. Tokyo, Tokyo, JPN) ,  SAITOH Shin-ichiroh (Univ. Tokyo, Tokyo, JPN) ,  SHIBATA Takuma (Univ. Tokyo, Tokyo, JPN) ,  TANIMURA Natsuko (Univ. Tokyo, Tokyo, JPN) ,  FUKUI Ryutaro (Univ. Tokyo, Tokyo, JPN) ,  MIYAKE Kensuke (Univ. Tokyo, Tokyo, JPN)
Material： International Immunology  (Int Immunol)
Volume： 27  Issue： 2  Page： 83-94  Publication year： Feb. 2015 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： ion channel ,...
Semi thesaurus term： PIKfyve ,...

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JST classification (3)： Immunological reaction in general  (ED03010T) ,  Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Reference (25)：

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• Christensen, S. R., Shupe, J., Nickerson, K., Kashgarian, M., Flavell, R. A. and Shlomchik, M. J. 2006. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25:417.

Terms in the title (6)： リソソーム ,  RNA輸送 ,  促進 ,  樹状細胞 ,  TLR7 ,  応答