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J-GLOBAL ID：201502214099098341   Reference number：15A0866742

Leukotriene E₄ induces MUC5AC release from human airway epithelial NCI-H292 cells

ロイコトリエンE₄はヒト気道上皮NCI-H292細胞からのMUC5ACの放出を誘導する

Author (4)： SHIRASAKI Hideaki (Sapporo Medical Univ., Hokkaido, JPN) ,  KANAIZUMI Etsuko (Sapporo Medical Univ., Hokkaido, JPN) ,  SEKI Nobuhiko (Sapporo Medical Univ., Hokkaido, JPN) ,  HIMI Tetsuo (Sapporo Medical Univ., Hokkaido, JPN)
Material： Allergology International  (Allergol Int)
Volume： 64  Issue： 2  Page： 169-174  Publication year： Apr. 2015 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： tumor cell ,...
Semi thesaurus term： *MUC5AC ,...

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JST classification (3)： Other hormones of verterbrates  (EB08070K) ,  Basic medicine on respiratory system  (GI01020H) ,  Biological function  (EB03040U)

Substance index (1)： Leukotriene E4

Reference (27)：

• 1. Shirasaki H. Cysteinyl leukotriene receptor CysLT1 as a novel therapeutic target for allergic rhinitis. Expert Opin Ther Targets 2008;12:415-23.
• 2. Lee TH, Woszczek G, Farooque SP. Leukotriene E4: perspective on the forgotton mediator. J Allergy Clin Immunol 2009;124:417-21.
• 3. Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, et al. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 1999;399: 789-93.
• 4. Heise CE, O'Dowd BF, Figueroa DJ, Sawyer N, Nguyen T, Im DS, et al. Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 2000;275: 30531-6.
• 5. Laitinen LA, Laitinen A, Haahtela Vilkka V, Spur BW, Lee T. Leukotriene E4 and granulocytic infiltration into asthmatic airways. Lancet 1993;341:989-90.

Terms in the title (7)： ロイコトリエンE4 ,  ヒト ,  気道上皮 ,  細胞 ,  MUC5AC ,  放出 ,  誘導