Art

J-GLOBAL ID：201502214706243682   Reference number：15A1024494

Inhibitory effect of bisphosphonate on osteoclast function contributes to improved skeletal pain in ovariectomized mice

卵巣摘出マウスの骨痛改善に寄与する破骨細胞機能に及ぼすビスホスホネートの抑制効果

Author (10)： ABE Yasuhisa (Sapporo Medical Univ. School of Medicine, Dep. of Orthopaedic Surgery, South 1, West 16, Chuo-ku, 060-8543, Sapporo, JPN) ,  IBA Kousuke (Sapporo Medical Univ. School of Medicine, Dep. of Orthopaedic Surgery, South 1, West 16, Chuo-ku, 060-8543, Sapporo, JPN) ,  SASAKI Koichi (Sapporo Medical Univ. School of Medicine, Dep. of Orthopaedic Surgery, South 1, West 16, Chuo-ku, 060-8543, Sapporo, JPN) ,  CHIBA Hironori (Sapporo Medical Univ. School of Medicine, Dep. of Orthopaedic Surgery, South 1, West 16, Chuo-ku, 060-8543, Sapporo, JPN) ,  KANAYA Kumiko (Sapporo Medical Univ. School of Medicine, Dep. of Orthopaedic Surgery, South 1, West 16, Chuo-ku, 060-8543, Sapporo, JPN) ,  KAWAMATA Tomoyuki (Shinsyu Univ. School of Medicine, Dep. of Anesthesiology and Resuscitology, Matsumoto, JPN) ,  ODA Kimimitsu (Niigata Univ. Graduate School of Medical and Dental Sciences, Div. of Biochemistry, Niigata, JPN) ,  AMIZUKA Norio (Hokkaido Univ. Graduate School of Dental Medicine, Dep. of Developmental Biology of Hard Tissue, Sapporo, JPN) ,  SASAKI Muneteru (Hokkaido Univ. Graduate School of Dental Medicine, Dep. of Developmental Biology of Hard Tissue, Sapporo, JPN) ,  YAMASHITA Toshihiko (Sapporo Medical Univ. School of Medicine, Dep. of Orthopaedic Surgery, South 1, West 16, Chuo-ku, 060-8543, Sapporo, JPN)
Material： Journal of Bone and Mineral Metabolism  (JBMM)
Volume： 33  Issue： 2  Page： 125-134  Publication year： Mar. 2015 
JST Material Number： L0163A  ISSN： 0914-8779  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： ovariectomy ,...
Semi thesaurus term： c-Fos ,...

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JST classification (3)： Basic medicine on musculoskeletal system  (GG01020B) ,  Basic therapeutics  (GC03012A) ,  Basic research of other drugs acting on metabolism  (GW13060I)

Substance index (1)： Alendronate

Reference (46)：

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• National Osteoporosis Foundation (2010) Clinician’s guide to prevention and treatment of osteoporosis. National Osteoporosis Foundation, Washington, DC
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• Iwamoto J, Takeda T, Sato Y, Uzawa M (2004) Effect of alendronate on metacarpal and lumbar bone mineral density, bone resorption and chronic back pain in postmenopausal women with osteoporosis. Clin Rheumatol 23:383-389
• Ghinoi V, Brandi ML (2002) Clodronate: mechanisms of action on bone remodeling and clinical use in osteometabolic disorders. Expert Opin Pharmacother 3:1643-1656

Terms in the title (6)： 卵巣摘出 ,  マウス ,  骨痛 ,  破骨細胞 ,  ビスホスホネート ,  抑制効果