Art

J-GLOBAL ID：201502214940922100   Reference number：15A0270153

Development and validation of a high-performance liquid chromatography method for the quantification of ursolic/oleanic acids mixture isolated from Plumeria obtusa

Plumeria obtusaから単離されたオレアノール酸/ウルソール酸混合物の定量のための高速液体クロマトグラフィーの開発と検証

Author (8)： ALVARADO Helen L. (Dep. of Pharmacy and Pharmaceutical Technol., Fac. of Pharmacy, Univ. of Barcelona, Joan XXIII Av. s/n, Barcelona ...) ,  ALVARADO Helen L. (Dep. of Physical Chemistry, Fac. of Pharmacy, Univ. of Barcelona, Joan XXIII Av. s/n, Barcelona 08028, ESP) ,  ABREGO Guadalupe (Dep. of Pharmacy and Pharmaceutical Technol., Fac. of Pharmacy, Univ. of Barcelona, Joan XXIII Av. s/n, Barcelona ...) ,  ABREGO Guadalupe (Dep. of Physical Chemistry, Fac. of Pharmacy, Univ. of Barcelona, Joan XXIII Av. s/n, Barcelona 08028, ESP) ,  GARDUNO-RAMIREZ Maria L. (Centro de Investigaciones Quimicas, Universidad Autonoma del Estado de Morelos, Av. Universidad No. 1001, Col ...) ,  CLARES Beatriz (Dep. of Pharmacy and Pharmaceutical Technol., Fac. of Pharmacy, Univ. of Granada, Campus de Cartuja St. s/n, Granada ...) ,  GARCIA Maria L. (Dep. of Physical Chemistry, Fac. of Pharmacy, Univ. of Barcelona, Joan XXIII Av. s/n, Barcelona 08028, ESP) ,  CALPENA Ana C. (Dep. of Pharmacy and Pharmaceutical Technol., Fac. of Pharmacy, Univ. of Barcelona, Joan XXIII Av. s/n, Barcelona ...)
Material： Journal of Chromatography B  (Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences)
Volume： 983-984  Page： 111-116  Publication year： Mar. 01, 2015 
JST Material Number： W0571A  ISSN： 1570-0232  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Apocynaceae ,  quantitative analysis(analytical chemistry) ,  *high performance liquid chromatography ,  triterpene ,  detection limit ,  quantitation limits ,  accuracy ,  standard deviation ,  test ,  olefin compound ,  alicyclic alcohol ,  pentacyclic triterpene ,  secondary alcohol ,  unsaturated carboxylic acid
Semi thesaurus term： *Plumeria obtusa ,  relative standard deviation ,  verification test

JST classification (2)： Analysis of drugs  (GV01040Q) ,  Liquid chromatography  (CC04014L)

Substance index (2)： Oleanolic acid ,  Ursolic acid

Reference (22)：

• M.N. Laszczyk, Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy, Planta Med. 75 (2009) 1549-1560.
• H. Sheng, H. Sun, Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases, Nat. Prod. Rep. 28 (3) (2011) 543-593.
• L.O. Somova, A. Nadar, P. Rammanan, F.O. Shode, Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension, Phytomedicine 10 (2003) 115-121.
• J. Liu, Oleanolic acid and ursolic acid: research perspectives, J. Ethnopharmacol. 100 (2005) 92-94.
• X. Wang, X.L. Ye, R. Liu, H.L. Chen, H. Bai, X. Liang, X.D. Zhang, Z. Wang, W.L. Li, C.X. Hai, Antioxidant activities of oleanolic acid in vitro: possible role of Nrf2 and MAP kinases, Chem. Biol. Interact. 184 (2010) 328-337.

Terms in the title (8)： 単離 ,  オレアノール酸 ,  ウルソール酸 ,  混合物 ,  定量 ,  高速液体クロマトグラフィー ,  開発 ,  検証