Art

J-GLOBAL ID：201502216048850513   Reference number：15A1304914

Subattomole detection of adiponectin in urine by ultrasensitive ELISA coupled with thio-NAD cycling

チオ-NADサイクリングと共役した超高感度ELISAによる尿中アディポネクチンのサブアトモル検出

Author (10)： MORIKAWA Mika (R&D Headquarters, TAUNS Laboratories, Inc.) ,  MORIKAWA Mika (Kagawa School of Pharmaceutical Sciences, Tokushima Bunri Univ.) ,  NAITO Rina (Kagawa School of Pharmaceutical Sciences, Tokushima Bunri Univ.) ,  MITA Koichi (Fac. of Sci. and Engineering, Tokushima Bunri Univ.) ,  WATABE Satoshi (R&D Dep., BL Co. Ltd.) ,  NAKAISHI Kazunari (R&D Headquarters, TAUNS Laboratories, Inc.) ,  YOSHIMURA Teruki (Fac. of Pharmaceutical Sciences, Health Sciences Univ. of Hokkaido) ,  MIURA Toshiaki (Graduate School of Pharmaceutical Sciences, Hokkaido Univ.) ,  HASHIDA Seiichi (Inst. for Health Sciences, Tokushima Bunri Univ.) ,  ITO Etsuro (Kagawa School of Pharmaceutical Sciences, Tokushima Bunri Univ.)
Material： Biophysics and Physicobiology (Web)  (Biophys Physicobiology (Web))
Volume： 12  Page： 79-86 (J-STAGE)  Publication year： 2015 
JST Material Number： U0030A  ISSN： 2189-4779  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *ELISA ,...

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JST classification (2)： Bioassay  (EA03060N) ,  Cytokines  (EB08090G)

Substance index (2)： NAD ,  Creatinine

Reference (38)：

• [1] Matsuzawa, Y., Funahashi, T. & Nakamura, T. Molecular mechanism of metabolic syndrome X: contribution of adipocytokines·adipocyte-derived bioactive substances. Ann. N.Y. Acad. Sci. 892, 146-154 (1999).
• [2] Cnop, M., Havel, P. J., Utzschneider, K. M., Carr, D. B., Sinha, M. K., Boyko, E. J., et al. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia 46, 459-469 (2003).
• [3] Ouchi, N., Kihara, S., Arita, Y., Maeda, K., Kuriyama, H., Okamoto, Y., et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100, 2473-2476 (1999).
• [4] Hotta, K., Funahashi, T., Arita, Y., Takahashi, M., Matsuda, M., Okamoto, Y., et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler. Thromb. Vasc. Biol. 20, 1595-1599 (2000).
• [5] Ix, J. H. & Sharma, K. Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: the roles of fetuin-A, adiponectin, and AMPK. J. Am. Soc. Nephrol. 21, 406-412 (2010).

Terms in the title (7)： NAD ,  サイクリング ,  共役 ,  高感度 ,  ELISA ,  尿 ,  アディポネクチン