Art

J-GLOBAL ID：201502216855318221   Reference number：15A1024776

Chemical constituents isolated from Juncus effusus induce cytotoxicity in HT22 cells

Juncus effususから分離した化学成分はHT22細胞において細胞毒性を誘導する

Author (7)： ISHIUCHI Kan'Ichiro (Nihon Univ., School of Pharmacy, 7-7-1, Narashinodai, 274-8555, Funabashi, Chiba, JPN) ,  KOSUGE Yasuhiro (Nihon Univ., Lab. of Pharmacology, School of Pharmacy, 7-7-1, Narashinodai, 274-8555, Funabashi, Chiba, JPN) ,  HAMAGAMI Hazuki (Nihon Univ., School of Pharmacy, 7-7-1, Narashinodai, 274-8555, Funabashi, Chiba, JPN) ,  OZAKI Mayu (Nihon Univ., School of Pharmacy, 7-7-1, Narashinodai, 274-8555, Funabashi, Chiba, JPN) ,  ISHIGE Kumiko (Nihon Univ., Lab. of Pharmacology, School of Pharmacy, 7-7-1, Narashinodai, 274-8555, Funabashi, Chiba, JPN) ,  ITO Yoshihisa (Nihon Univ., Lab. of Pharmacology, School of Pharmacy, 7-7-1, Narashinodai, 274-8555, Funabashi, Chiba, JPN) ,  KITANAKA Susumu (Nihon Univ., School of Pharmacy, 7-7-1, Narashinodai, 274-8555, Funabashi, Chiba, JPN)
Material： Journal of Natural Medicines  (J Nat Med)
Volume： 69  Issue： 3  Page： 421-426  Publication year： Jul. 2015 
JST Material Number： L5856A  ISSN： 1340-3443  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： neuron ,...
Semi thesaurus term： MTT assay

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JST classification (2)： Phenanthrenes  (CF06070G) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (12)： 3,4-Dimethyl-5-hydroxy-5-pentyl-2(5H)-furanone ,  9,10-Dihydrophenanthrene ,  Effususol A ,  Effusol ,  Juncuenin B ,  Juncuenin D ,  Juncusol ,  Dehydroeffusol ,  Dehydrojuncuenin B ,  Dehydrojuncusol ,  Luteolin ,  2-(3,4-Dihydroxyphenyl)-5-methoxy-7-hydroxy-4H-1-benzopyran-4-one

Reference (19)：

• Nanba T (1980) Coloured illustrations of Wakan-Yaku, vol 2. Hoikusha Publishing, Osaka, p 19
• Shima K, Toyota M, Asakawa Y (1991) Phenanthrene derivatives from the medullae of Juncus effusus. Phytochemistry 30:3149–3151
• Greca MD, Fiorentino A, Mangoni L, Molinaro A, Monaco P, Previtera L (1992) 9,10-Dihydrophenanthrene metabolites from Juncus effusus L. Tetrahedron Lett 33:5257–5260
• Yang GZ, Li HX, Song FJ, Chen Y (2007) Diterpenoid and phenolic compounds from Juncus effusus L. Helv Chim Acta 90:1289–1295
• Della MG, Fiorentino A, Molinaro A, Monaco P, Previtera L (1993) A bioactive dihydrodibenzoxepin from Juncus effusus. Phytochemistry 34:1182–1184

Terms in the title (5)： Juncus ,  化学成分 ,  HT22細胞 ,  細胞毒性 ,  誘導