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J-GLOBAL ID：201502217950009232   Reference number：15A1014136

Pharmacokinetics study of once-daily intravenous busulfan in conditioning regimens for hematopoietic stem cell transplantation

造血幹細胞移植のための条件づけレジメンにおける1日1回の静脈内ブスルファンの薬物動態研究

Author (24)： SATO Miki (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  KAKO Shinichi (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  MATSUMOTO Kana (Doshisha Women’s Coll. of Liberal Arts, Dep. of Clinical Pharmaceutics, Fac. of Pharmaceutical Sciences, Kyoto, JPN) ,  OSHIMA Kumi (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  AKAHOSHI Yu (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  NAKANO Hirofumi (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  UGAI Tomotaka (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  YAMASAKI Ryoko (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  WADA Hidenori (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  ISHIHARA Yuko (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  SAKAMOTO Kana (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  KAWAMURA Koji (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  ASHIZAWA Masahiro (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  TERASAKO-SAITO Kiriko (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  KIMURA Shun-Ichi (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  NAKASONE Hideki (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  KIKUCHI Misato (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  TANIHARA Aki (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  YAMAZAKI Rie (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  TANAKA Yukie (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  KANDA Junya (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  NISHIDA Junji (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...) ,  MORITA Kunihiko (Doshisha Women’s Coll. of Liberal Arts, Dep. of Clinical Pharmaceutics, Fac. of Pharmaceutical Sciences, Kyoto, JPN) ,  KANDA Yoshinobu (Jichi Medical Univ., Div. of Hematology, Saitama Medical Center, 1-847 Amanuma, Omiya-ku, 330-8503, Saitama, Saitama ...)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 101  Issue： 5  Page： 497-504  Publication year： May. 2015 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *hematopoietic stem cell transplantation ,...
Semi thesaurus term： Jones-Mote type hypersensitivity ,...

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JST classification (2)： Physicochemical characteristics of drugs  (GV01060M) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (1)： Busulfan

Reference (29)：

• Bredeson C, LeRademacher J, Kato K, Dipersio JF, Agura E, Devine SM, et al. Prospective cohort study comparing intravenous busulfan to total body irradiation in hematopoietic cell transplantation. Blood. 2013;122:3871-8.
• Fuji S, Ueno N, Hiramoto N, Asakura Y, Yakushijin K, Kamiyama Y, et al. Reduced-intensity conditioning regimen with low-dose ATG-F for unrelated bone marrow transplant is associated with lower non-relapse mortality than a regimen with low-dose TBI: a single-center retrospective analysis of 103 cases. Int J Hematol. 2013;98:608-14.
• Copelan EA, Bechtel TP, Avalos BR, Elder PJ, Ezzone SA, Scholl MD, et al. Busulfan levels are influenced by prior treatment and are associated with hepatic veno-occlusive disease and early mortality but not with delayed complications following marrow transplantation. Bone Marrow Transplant. 2001;27:1121-4.
• Dix SP, Wingard JR, Mullins RE, Jerkunica I, Davidson TG, Gilmore CE, et al. Association of busulfan area under the curve with veno-occlusive disease following BMT. Bone Marrow Transplant. 1996;17:225-30.
• Slattery JT, Clift RA, Buckner CD, Radich J, Storer B, Bensinger WI, et al. Marrow transplantation for chronic myeloid leukemia: the influence of plasma busulfan levels on the outcome of transplantation. Blood. 1997;89:3055-60.

Terms in the title (7)： 造血幹細胞移植 ,  条件づけ ,  レジメン ,  静脈 ,  ブスルファン ,  薬物動態 ,  研究