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J-GLOBAL ID:201502218516900828   Reference number:15A1289190

Pemetrexed-Induced Rash May Be Prevented by Supplementary Corticosteroids

ペメトレキセド誘発性発疹は補充性コルチコステロイドにより予防できるかもしれない
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Volume: 38  Issue: 11  Page: 1752-1756 (J-STAGE)  Publication year: 2015 
JST Material Number: S0989A  ISSN: 0918-6158  CODEN: BPBLEO  Document type: Article
Article type: 原著論文  Country of issue: Japan (JPN)  Language: ENGLISH (EN)
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Clinical dermatology in general 
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Reference (30):
  • 1) Shih C, Habeck LL, Mendelsohn LG, Chen VJ, Schultz RM. Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA). Adv. Enzyme Regul., 38, 135-152 (1998).
  • 2) Taylor EC, Patel HH. Synthesis of pyrazolo[3,4-d]pyrimidine analogues of the potent antitumor agent N-4-[2-(2-amino-4(3H)-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl-L-glutamic acid (LY231514). Tetrahedron, 48, 8089-8100 (1992).
  • 3) Rusthoven JJ, Eisenhauer E, Butts C, Gregg R, Dancey J, Fisher B, Iglesias J. Multitargeted antifolate LY231514 as first-line chemotherapy for patients with advanced non-small-cell lung cancer: A phase II study. National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol., 17, 1194 (1999).
  • 4) Vogelzang NJ, Rusthoven JJ, Symanowski J, Denham C, Kaukel E, Ruffie P, Gatzemeier U, Boyer M, Emri S, Manegold C, Niyikiza C, Paoletti P. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J. Clin. Oncol., 21, 2636-2644 (2003).
  • 5) Hanauske AR, Chen V, Paoletti P, Niyikiza C. Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors. Oncologist, 6, 363-373 (2001).
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