Art

J-GLOBAL ID：201502218893189187   Reference number：15A1060718

Safeguarding gene drive experiments in the laboratory Multiple stringent confinement strategies should be used whenever possible

実験室における保護された遺伝子ドライブ実験 可能な限り複合的な厳しい封込め戦略が使用されるべきである

Author (28)： AKBARI Omar S. (Univ. California, CA, USA) ,  BELLEN Hugo J. (Baylor Coll. Medicine, TX, USA) ,  BIER Ethan (Univ. California, CA, USA) ,  BULLOCK Simon L. (Medical Res. Council Lab. Molecular Biology, Cambridge, GBR) ,  BURT Austin (Imperial Coll. London, Berks, GBR) ,  CHURCH George M. (Harvard Medical School, MA, USA) ,  COOK Kevin R. (Indiana Univ., IN, USA) ,  DUCHEK Peter (Inst. Molecular Biotechnology, Austrian Acad. Sci., Vienna, AUT) ,  EDWARDS Owain R. (CSIRO Centre for Environment and Life Sci., WA, AUS) ,  ESVELT Kevin M. (Harvard Medical School, MA, USA) ,  GANTZ Valentino M. (Univ. California, CA, USA) ,  GOLIC Kent G. (Univ. Utah, UT, USA) ,  GRATZ Scott J. (Univ. Wisconsin-Madison, WI, USA) ,  HARRISON Melissa M. (Univ. Wisconsin-Madison, WI, USA) ,  HAYES Keith R. (CSIRO Biosecurity Flagship, Tasmania, AUS) ,  JAMES Anthony A. (Univ. California at Irvine, CA, USA) ,  KAUFMAN Thomas C. (Indiana Univ., IN, USA) ,  KNOBLICH Juergen (Inst. Molecular Biotechnology, Austrian Acad. Sci., Vienna, AUT) ,  MALIK Harmit S. (Fred Hutchinson Cancer Res. Center, WA, USA) ,  MATTHEWS Kathy A. (Indiana Univ., IN, USA) ,  O'CONNOR-GILES Kate M. (Univ. Wisconsin-Madison, WI, USA) ,  PARKS Annette L. (Indiana Univ., IN, USA) ,  PERRIMON Norbert (Harvard Medical School, MA, USA) ,  PORT Fillip (Medical Res. Council Lab. Molecular Biology, Cambridge, GBR) ,  RUSSELL Steven (Univ. Cambridge, Cambridgeshire, GBR) ,  UEDA Ryu (Graduate Univ. Advanced Studies, Shizuoka, JPN) ,  UEDA Ryu (National Inst. Genetics, Shizuoka, JPN) ,  WILDONGER Jill (Univ. Wisconsin-Madison, WI, USA)
Material： Science
Volume： 349  Issue： 6251  Page： 927-929  Publication year： Aug. 28, 2015 
JST Material Number： E0078A  ISSN： 0036-8075  CODEN： SCIEA  Document type： Article
Article type： 解説  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： gene manipulation ,  RNA ,  *endonuclease ,  *gene expression ,  palindrome ,  population dynamics ,  stability ,  Public Health ,  sustainable agriculture ,  environmental conservation ,  *CRISPR-Cas Systems ,  D. melanogaster ,  genetic stability ,  Drosophila ,  Anopheles ,  CRISPR ,  *molecular genetic phenomenon ,  information ,  genetic information ,  nucleotide sequence ,  sequence and arrangement ,  Agriculture ,  Diptera ,  invertebrate
Semi thesaurus term： Drosophila ,  Anopheles ,  *Cas9遺伝子 ,  Clustered Regularly Interspaced Short Palindromic Repeats ,  遺伝子ドライブ

JST classification (1)： Gene manipulation  (EC02050B)

Terms in the title (6)： 実験室 ,  遺伝子 ,  ドライブ ,  実験 ,  封込め ,  戦略