Art

J-GLOBAL ID：201502219115585976   Reference number：15A0709047

Evaluation of the effects of amyloid β aggregation from seaweed extracts by a microliter-scale high-throughput screening system with a quantum dot nanoprobe

量子ドットナノプローブを用いるマイクロリットルスケールのハイスループットスクリーニングシステムによる海藻抽出物由来のアミロイドβ凝集効果の評価

Author (5)： OGARA Toshiki (Dep. of Applied Sciences, Muroran Inst. of Technol., 27-1 Mizumoto-cho, Muroran, Hokkaido 050-8585, JPN) ,  TAKAHASHI Tomohito (Dep. of Applied Sciences, Muroran Inst. of Technol., 27-1 Mizumoto-cho, Muroran, Hokkaido 050-8585, JPN) ,  YASUI Hajime (Lab. of Marine Industrial Sci. and Technol., Fac. of Fisheries Sciences, Hokkaido Univ., Hakodate, Hokkaido 041-8611 ...) ,  UWAI Koji (Dep. of Applied Sciences, Muroran Inst. of Technol., 27-1 Mizumoto-cho, Muroran, Hokkaido 050-8585, JPN) ,  TOKURAKU Kiyotaka (Dep. of Applied Sciences, Muroran Inst. of Technol., 27-1 Mizumoto-cho, Muroran, Hokkaido 050-8585, JPN)
Material： Journal of Bioscience and Bioengineering
Volume： 120  Issue： 1  Page： 45-50  Publication year： Jul. 2015 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： quantum dot ,...
Semi thesaurus term： high throughput screening ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=15A0709047&from=J-GLOBAL&jstjournalNo=G0535B") }}

JST classification (3)： Proteins and peptides in general  (EB03010N) ,  Plant biochemistry  (EH01050J) ,  Marine algae(=seaweeds)  (FJ13030N)

Reference (16)：

• Brookmeyer, R., Johnson, E., Ziegler-Graham, K., and Arrighi, H. M.: Forecasting the global burden of Alzheimer's disease, Alzheimers Dement., 3, 186-191 (2007).
• Masters, C. L, Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L, and Beyreuther, K.: Amyloid plaque core protein in Alzheimer disease and Down syndrome, Proc. Natl. Acad. Sci. USA, 82, 4245-4249 (1985).
• Hardy, J. and Selkoe, D. J.: The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics, Science, 297, 353-356 (2002).
• Lesne, S., Koh, M. T., Kotilinek, L, Kayed, R., Glabe, C. G., Yang, A., Gallagher, M., and Ashe, K. H.: A specific amyloid-beta protein assembly in the brain impairs memory, Nature, 440, 352-357 (2006).
• Shankar, G. M., Li, S., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., Brett, F. M., Farrell, M. A., Rowan, M. J., Lemere, C. A., and other X authors: Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory, Nat. Med., 14, 837-842 (2008).

Terms in the title (7)： 量子ドット ,  ナノプローブ ,  ハイスループットスクリーニング ,  海藻抽出物 ,  アミロイドβ ,  凝集効果 ,  評価