Art

J-GLOBAL ID：201502219477194992   Reference number：15A1268280

Aging, clonal hematopoiesis and preleukemia: not just bad luck?

加齢,クローン性造血および前白血病:不運だけではない?

Author (5)： SHLUSH Liran I. (Univ. Health Network (UHN), Dep. of Medical Oncology and Hematology, Princess Margaret Cancer Centre, 610 Univ. Ave ...) ,  SHLUSH Liran I. (Weizmann Inst. of Sci., Rehovot, ISR) ,  ZANDI Sasan (Univ. Health Network (UHN), Dep. of Medical Oncology and Hematology, Princess Margaret Cancer Centre, 610 Univ. Ave ...) ,  ITZKOVITZ Shalev (Weizmann Inst. of Sci., Rehovot, ISR) ,  SCHUH Andre C. (Univ. Health Network (UHN), Dep. of Medical Oncology and Hematology, Princess Margaret Cancer Centre, 610 Univ. Ave ...)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 102  Issue： 5  Page： 513-522  Publication year： Nov. 2015 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 文献レビュー  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *aging (physiology) ,...
Semi thesaurus term： *Preleukemia

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JST classification (2)： Carcinogenic mechanisms and factors  (GE02020C) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Reference (47)：

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• Corces-Zimmerman MR, et al. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci USA. 2014;111(7):2548-53.
• Jan M, et al. Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med. 2012;4(149):149ra118.
• Miyamoto T, Weissman IL, Akashi K. AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation. Proc Natl Acad Sci USA. 2000;97(13):7521-6.
• Shlush LI, et al. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature. 2014;506(7488):328-33.

Terms in the title (3)： 加齢 ,  クローン性造血 ,  前白血病