Art

J-GLOBAL ID：201502219645794631   Reference number：15A1289277

Synthesis and Antiviral Evaluation of Some C₃-Symmetrical Trialkoxy-Substituted 1,3,5-Triazines and Their Molecular Geometry

いくつかのC₃-対称トリアルコキシ-置換1,3,5-トリアジン類の合成と抗ウイルス評価およびそれらの分子形状

Author (12)： MIBU Nobuko (Fac. of Pharmaceutical Sciences, Fukuoka Univ.) ,  YOKOMIZO Kazumi (Fac. of Pharmaceutical Sciences, Sojo Univ.) ,  AKI Hatsumi (Fac. of Pharmaceutical Sciences, Fukuoka Univ.) ,  OTA Norimasa (Fac. of Pharmaceutical Sciences, Fukuoka Univ.) ,  FUJII Hiroyuki (Fac. of Pharmaceutical Sciences, Fukuoka Univ.) ,  YUZURIHA Ai (Fac. of Pharmaceutical Sciences, Fukuoka Univ.) ,  SANEYOSHI Shiori (Fac. of Pharmaceutical Sciences, Sojo Univ.) ,  TANAKA Aoi (Fac. of Pharmaceutical Sciences, Sojo Univ.) ,  KOGA Airi (Fac. of Pharmaceutical Sciences, Fukuoka Univ.) ,  ZHOU Jianrong (Fac. of Pharmaceutical Sciences, Sojo Univ.) ,  MIYATA Takeshi (Fac. of Pharmaceutical Sciences, Sojo Univ.) ,  SUMOTO Kunihiro (Fac. of Pharmaceutical Sciences, Fukuoka Univ.)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 63  Issue： 11  Page： 935-944 (J-STAGE)  Publication year： 2015 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *nitrogen heterocyclic compound ,  molecular structure ,  Structure-Activity Relationship ,  calorimetry ,  microorganism test ,  isothermal titration calorimetry ,  Human alphaherpesvirus 1 ,  *Triazines ,  Viral Plaque Assay ,  microorganism ,  Herpesviridae ,  animal virus
Semi thesaurus term： herpes simplex virus 1 ,  *Triazines ,  Plaque Assay ,  molecular geometry

JST classification (1)： Triazines  (CF07107M)

Substance index (10)： 2,4,6-Tris(2-methoxyethoxy)-1,3,5-triazine ,  2,4,6-Tris(pentyloxy)-1,3,5-triazine ,  2,4,6-Tris(heptyloxy)-1,3,5-triazine ,  2,4,6-Triisopropoxy-1,3,5-triazine ,  2,4,6-Tris(cyclohexyloxy)-1,3,5-triazine ,  2,4,6-Tris(cycloheptyloxy)-1,3,5-triazine ,  2,4,6-Tris(1,3-benzodioxole-5-yloxy)-1,3,5-triazine ,  2,4,6-Tris(cyclopentyloxy)-1,3,5-triazine ,  2,4,6-Tris[3-(trifluoromethyl)phenoxy]-1,3,5-triazine ,  2,4,6-Tris[4-(trifluoromethyl)phenoxy]-1,3,5-triazine

Reference (30)：

• 1) Varki A., Cummings R. D., Esko J. D., Freeze H. H., Stanley P., Bertozzi C. R., Hart G. W., Etzler M. E., “Essentials of Glycobiology,” 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 2009, p. 719 and related cited therein.
• 2) Sansone F., Casnati A., Chem. Soc. Rev., 42, 4623-4639 (2013).
• 3) Reitsma S., Slaaf D. W., Vink H., van Zandvoort M. A. M. J., Pflugers Arch. Eur. J. Physiol., 454, 345-359 (2007).
• 4) Camille G. W., “The Practice of Medicinal Chemistry,” 3rd ed., Academic Press, San Diego, 2008 and related cited therein.
• 5) Humblet V., Misra P., Bhushan K. R., Nasr K., Ko Y.-S., Tsukamoto T., Pannier N., Frangioni J. V., Maison W., J. Med. Chem., 52, 544-550 (2009).

Terms in the title (7)： C3 ,  対称 ,  置換 ,  トリアジン類 ,  ウイルス ,  評価 ,  分子形状