Current status of the development of Ras inhibitors

SHIMA Fumi; MATSUMOTO Shigeyuki; YOSHIKAWA Yoko; KAWAMURA Takashi; ISA Masayuki; KATAOKA Tohru

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J-GLOBAL ID：201502220027700284 Reference number：15A0974666

Current status of the development of Ras inhibitors

Ras阻害剤の開発の現状

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Material：
Volume： 158 Issue： 2 Page： 91-99 Publication year： Aug. 2015
JST Material Number： W1920A ISSN： 0021-924X CODEN： JOBIAO Document type： Article
Article type：文献レビュー Country of issue： United Kingdom (GBR) Language： ENGLISH (EN)

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Basic research of antitumor(=antineoplastic)drugs , Biological function

Reference (62)：

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Knrnoub, A.E. and Weinberg, R.A. (2008) Ras oncogenes: split personalities. Nat. Rev. Mol. Cell Biol. 9, 517-531
Vetter, I.R. and Wittinghofer, A. (2001) The guanine nucleotide-binding switch in three dimensions. Science 294, 1299-1304
Repasky, G.A., Chenette, E.J., and Der, C.J. (2004) Renewing the conspiracy theory debate: does Raf function alone to mediate Ras oncogenesis? Trends Cell Biol. 14, 639-647
Weinstein, B. (2002) Addiction to oncogenes-the Achilles heel of cancer. Science 297, 63-64

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