Art

J-GLOBAL ID：201502221035730202   Reference number：15A1356286

Improvements in Signs and Symptoms of Dry Eye after Instillation of 2% Rebamipide

2%レバミピド点眼後のドライアイの兆候と症状の改善

Author (10)： IGARASHI Tsutomu (Dep. of Ophthalmology, Nippon Medical School) ,  FUJITA Miho (Dep. of Ophthalmology, Nippon Medical School) ,  YAMADA Yumi (Dep. of Ophthalmology, Nippon Medical School) ,  KOBAYASHI Maika (Dep. of Ophthalmology, Nippon Medical School) ,  FUJIMOTO Chiaki (Dep. of Ophthalmology, Nippon Medical School) ,  TAKAHASHI Hisatomo (Dep. of Ophthalmology, Nippon Medical School) ,  IGARASHI Toru (Dep. of Pediatrics, Nippon Medical School) ,  NAKANO Yuichiro (Dep. of Ophthalmology, Nippon Medical School Musashi Kosugi Hospital) ,  SUZUKI Hisaharu (Dep. of Ophthalmology, Nippon Medical School Musashi Kosugi Hospital) ,  TAKAHASHI Hiroshi (Dep. of Ophthalmology, Nippon Medical School)
Material： Journal of Nippon Medical School  (日本医科大学雑誌)
Volume： 82  Issue： 5  Page： 229-236 (J-STAGE)  Publication year： 2015 
JST Material Number： F0887A  ISSN： 1345-4676  CODEN： JNMSF5  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： drug for peptic ulcer ,...
Semi thesaurus term： *Prognostic diagnosis ,...

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JST classification (2)： Drug therapy(=pharmacotherapy)for eye diseases  (GP05020E) ,  Clinical application of drugs acting on sensory organs  (GW04070V)

Substance index (2)： Rebamipide ,  Fluorecein

Reference (40)：

• 1. The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 2007; 5: 93-107.
• 2. Urashima H, Takeji Y, Okamoto T, Fujisawa S, Shinohara H: Rebamipide increases mucin-like substance contents and periodic acid Schiff reagent-positive cells density in normal rabbits. J Ocul Pharmacol Ther 2012; 28: 264-270.
• 3. Fujihara T, Murakami T, Nagano T, Nakamura M, Nakata K: INS365 suppresses loss of corneal epithelial integrity by secretion of mucin-like glycoprotein in a rabbit short-term dry eye model. J Ocul Pharmacol Ther 2002; 18: 363-370.
• 4. Iijima K, Ichikawa T, Okada S, Ogawa M, Koike T, Ohara S, Shimosegawa T: Rebamipide, a cytoprotective drug, increases gastric mucus secretion in human: evaluations with endoscopic gastrin test. Dig Dis Sci 2009; 54: 1500-1507.
• 5. Naito Y, Yoshikawa T: Rebamipide: a gastrointestinal protective drug with pleiotropic activities. Expert Rev Gastroenterol Hepatol 2010; 4: 261-270.

Terms in the title (5)： レバミピド ,  点眼 ,  ドライアイ ,  兆候 ,  症状