Art

J-GLOBAL ID：201502221105173918   Reference number：15A0953501

Systematic Asymmetric Synthesis of All Diastereomers of (-)-Talaumidin and Their Neurotrophic Activity

(-)-タラウミジンの全ジアステレオマの系系的不斉合成とそれらの神経栄養性活性

Author (7)： HARADA Kenichi (Tokushima Bunri Univ., Tokushima, JPN) ,  KUBO Miwa (Tokushima Bunri Univ., Tokushima, JPN) ,  HORIUCHI Hiroki (Tokushima Bunri Univ., Tokushima, JPN) ,  ISHII Akiko (Tokushima Bunri Univ., Tokushima, JPN) ,  ESUMI Tomoyuki (Tokushima Bunri Univ., Tokushima, JPN) ,  HIOKI Hideaki (Gunma Univ., Gunma, JPN) ,  FUKUYAMA Yoshiyasu (Tokushima Bunri Univ., Tokushima, JPN)
Material： Journal of Organic Chemistry  (J Org Chem)
Volume： 80  Issue： 14  Page： 7076-7088  Publication year： Jul. 17, 2015 
JST Material Number： C0328A  ISSN： 0022-3263  CODEN： JOCEAH  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： asymmetric synthesis ,  molecular structure ,  *Aristolochiaceae ,  *cyclic ether ,  *oxygen heterocyclic compound ,  aldol reaction ,  hydroboration ,  deoxygenation ,  Mitsunobu reaction ,  aromatic compound ,  *secondary metabolite ,  *stereoselective reaction ,  diastereomer ,  growth ,  lignan
Semi thesaurus term： *Aristolochia arcuata ,  *tetrahydrofuran derivative ,  Biphenyl Compounds ,  neurite elongation

JST classification (4)： Plant biochemistry  (EH01050J) ,  Other natural substances of biological origin  (CF10090R) ,  Furans  (CF07072V) ,  Stereochemistry of organic reaction  (CF02130V)

Substance index (16)： Talaumidin ,  2-Methoxy-4-[(2S)-3β,4α-dimethyl-5α-(1,3-benzodioxole-5-yl)tetrahydrofuran-2α-yl]phenol ,  (2S,3S,4r,5S)-2-(3-Methoxy-4-hydroxyphenyl)-3,4-dimethyl-5-(1,3-benzodioxole-5-yl)tetrahydrofuran ,  Lignans machilin F ,  Chicanin ,  2-Methoxy-4-[(2S)-3α,4α-dimethyl-5α-(1,3-benzodioxole-5-yl)tetrahydrofuran-2α-yl]phenol ,  2-Methoxy-4-[(2S)-3α,4β-dimethyl-5β-(1,3-benzodioxole-5-yl)tetrahydrofuran-2α-yl]phenol ,  2-Methoxy-4-[(2S)-3α,4β-dimethyl-5α-(1,3-benzodioxole-5-yl)tetrahydrofuran-2α-yl]phenol ,  (4S)-3-[(2R,3S)-2-Methyl-3-hydroxy-3-[3-methoxy-4-(benzyloxy)phenyl]propionyl]-4-benzyloxazolidine-2-one ,  (4S)-3-[(2S,3S)-2-Methyl-3-hydroxy-3-[3-methoxy-4-(benzyloxy)phenyl]propanoyl]-4β-benzyloxazolidine-2-one ,  (4S)-2,3-Dimethyl-4-(tert-butyldimethylsilyloxy)-4-(3-methoxy-4-benzyloxyphenyl)butane-1-ol ,  (2S,3R,4S)-2,3-Dimethyl-4-(tert-butyldimethylsilyloxy)-4-(3-methoxy-4-benzyloxyphenyl)butanal ,  (3S)-2-Methyl-3-(tert-butyldimethylsilyloxy)-3-(3-methoxy-4-benzyloxyphenyl)propane-1-ol ,  (3S)-2-Methyl-3-(tert-butyldimethylsilyloxy)-3-(3-methoxy-4-benzyloxyphenyl)propanal ,  (4S)-3-Methyl-4-(tert-butyldimethylsilyloxy)-4-(3-methoxy-4-benzyloxyphenyl)butane-2-one ,  (1S)-1-(tert-Butyldimethylsilyloxy)-1-(3-methoxy-4-benzyloxyphenyl)-2,3-dimethyl-3-butene

Terms in the title (7)： タラウミジン ,  ジアステレオマ ,  系 ,  不斉合成 ,  神経 ,  栄養 ,  活性