Art

J-GLOBAL ID：201502250590473737   Reference number：15A0406025

Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases

癌や心臓血管疾患を予防するめのヘスペリジンおよびヘスペレチンの生物学的作用の背後にある分子機構

Author (9)： ROOHBAKHSH Ali (Pharmaceutical Res. Center, School of Pharmacy, Mashhad Univ. of Medical Sciences, Mashhad, IRN) ,  PARHIZ Hamideh (Pharmaceutical Res. Center, School of Pharmacy, Mashhad Univ. of Medical Sciences, Mashhad, IRN) ,  PARHIZ Hamideh (Dep. of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad Univ. of Medical Sciences, Mashhad, IRN) ,  SOLTANI Fatemeh (Dep. of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad Univ. of Medical Sciences, Mashhad, IRN) ,  SOLTANI Fatemeh (Biotechnology Res. Center, School of Pharmacy, Mashhad Univ. of Medical Sciences, Mashhad, IRN) ,  SOLTANI Fatemeh (Dep. of molecular sciences, School of Medicine, North Khorasan Univ. of Medical Sciences, Bojnurd, IRN) ,  REZAEE Ramin (Pharmaceutical Res. Center, School of Pharmacy, Mashhad Univ. of Medical Sciences, Mashhad, IRN) ,  REZAEE Ramin (Dep. of molecular sciences, School of Medicine, North Khorasan Univ. of Medical Sciences, Bojnurd, IRN) ,  IRANSHAHI Mehrdad (Biotechnology Res. Center, School of Pharmacy, Mashhad Univ. of Medical Sciences, Mashhad, IRN)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 124  Page： 64-74  Publication year： Mar. 01, 2015 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 文献レビュー  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *cardiovascular disease ,  *tumor ,  *prevention ,  vitamin P ,  *flavonoid ,  *mechanism ,  *property ,  *characteristic ,  antitumor action ,  antioxidation ,  anti-inflammatory action ,  Apoptosis ,  caspase ,  oncoprotein ,  Bax protein ,  inhibition of multiplication ,  cyclooxygenase ,  matrix metalloproteinase ,  Myocardial Ischemia ,  Myocardial Infarction ,  Hypertension ,  *targeting ,  animal test ,  phenolic compound ,  glycoside (except carbohydrate) ,  pyranoside ,  phenol ether ,  diol ,  hydroxy ketone ,  oxygen heterocyclic compound ,  polyphenol ,  *molecular mechanism ,  BCL-2 ,  angiogenesis inhibition ,  *molecular targeting ,  *biological property ,  anti-metastatic activity ,  Cyclooxygenase 2 ,  Matrix Metalloproteinase 2
Semi thesaurus term： *biological properties ,  anti-metastatic effect ,  COX2 ,  MMP2 ,  Cardiac remodeling

JST classification (4)： Basic medicine on cardiovascular system  (GJ01020K) ,  Basic therapeutics  (GC03012A) ,  Experimental treatment for tumors  (GE02040Y) ,  Condensed derivatives of pyrane  (CF07093I)

Substance index (2)： Hesperidin ,  Hesperetin

Terms in the title (8)： 癌 ,  心臓血管疾患 ,  予防 ,  するめ ,  ヘスペリジン ,  ヘスペレチン ,  生物学 ,  分子機構