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J-GLOBAL ID：201502253486057690   Reference number：15A0309408

Phase 2a, randomized, double-blind, placebo-controlled, multicenter, parallel-group study of a H₄R-antagonist (JNJ-39758979) in Japanese adults with moderate atopic dermatitis

中等度のアトピー性皮膚炎の日本人成人におけるH₄R-拮抗剤(JNJ-39758979)の第2a相,無作為,二重盲検,プラセボ対照,多施設,平行群研究

Author (13)： MURATA Yoko (Res. & Dev., Janssen Pharmaceutical KK, Tokyo, JPN) ,  SONG Michael ,  KIKUCHI Hisayuki ,  HISAMICHI Katsuya ,  XU Xie L. ,  GREENSPAN Andrew ,  KATO Mai ,  CHIOU Chiun-Fang ,  KATO Takeshi ,  GUZZO Cynthia ,  THURMOND Robin L. ,  OHTSUKI Mamitaro ,  FURUE Masutaka
Material： Journal of Dermatology  (J Dermatol)
Volume： 42  Issue： 2  Page： 129-139  Publication year： Feb. 2015 
JST Material Number： W1578A  ISSN： 0385-2407  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *atopic dermatitis ,...
Semi thesaurus term： *JNJ-39758979 ,...

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JST classification (3)： Drug therapy(=pharmacotherapy)for skin diseases  (GF05020A) ,  Treatment for immunologic diseases,allergic diseases.  (GD04030Y) ,  Clinical application of drugs acting on integumentum commune  (GW12020J)

Reference (44)：

• Akdis CA, Akdis M, Bieber T et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. European Academy of Allergology; Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Group. Allergy 2006; 61: 969-987.
• Homey B, Steinhoff M, Ruzicka T, Leung DY. Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 2006; 118: 178-189.
• Bieber T. Atopic dermatitis. N Engl J Med 2008; 358: 1483-1494.
• Leung DY, Bieber T. Atopic dermatitis. Lancet 2003; 361: 151-160.
• Muto T, Hsieh SD, Sakurai Y et al. Prevalence of atopic dermatitis in Japanese adults. Br J Dermatol 2003; 148: 117-121.

Terms in the title (9)： アトピー性皮膚炎 ,  日本人 ,  成人 ,  拮抗剤 ,  二重盲検 ,  プラセボ ,  対照 ,  施設 ,  研究