Art

J-GLOBAL ID：201502253560325031   Reference number：15A0705121

A QM/MM study of the 5′-AMP DNA hydrolysis of aprataxin

アプラタキシンの5′-AMP DNA加水分解に関するQM/MM研究

Author (4)： HANAOKA Kyohei (Graduate School of Pure and Applied Sciences, Univ. of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, JPN) ,  TANAKA Wataru (Graduate School of Pure and Applied Sciences, Univ. of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, JPN) ,  KAYANUMA Megumi (Graduate School of Systems and Information Engineering, Univ. of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, JPN) ,  SHOJI Mitsuo (Graduate School of Pure and Applied Sciences, Univ. of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, JPN)
Material： Chemical Physics Letters  (Chem Phys Lett)
Volume： 631-632  Page： 16-20  Publication year： Jul. 01, 2015 
JST Material Number： B0824A  ISSN： 0009-2614  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *DNA binding protein ,  *nuclear protein ,  *hydrolysis ,  *DNA repair enzyme ,  catalytic reaction ,  multistep process ,  elimination reaction ,  activation energy ,  phosphorylation ,  synthetic intermediate ,  quantum theory ,  molecular dynamics ,  computer simulation ,  protonation ,  adenine nucleotide ,  ribonucleotide ,  amino acid ,  nitrogen heterocyclic compound ,  primary amine
Semi thesaurus term： aprataxin ,  deadenylation ,  quantum mechanics

JST classification (2)： Nucleic acids in general  (EB04010U) ,  Enzyme in general  (EB09010D)

Substance index (2)： AMP ,  Histidine

Terms in the title (5)： アプラタキシン ,  5′-AMP ,  DNA ,  加水分解 ,  研究