Art

J-GLOBAL ID：201502257161057320   Reference number：15A0357985

Graft of the gelatin sponge scaffold containing genetically-modified neural stem cells promotes cell differentiation, axon regeneration, and functional recovery in rat with spinal cord transection

遺伝子修飾した神経幹細胞を含むゼラチンスポンジ足場移植片は,脊髄離断のあるラットで細胞分化,軸索再生および機能的回復を促進する

Author (8)： DU Bao-Ling (Dep. of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen Univ., Guangzhou, Guangdong, CHN) ,  ZENG Xiang ,  MA Yuan-Huan ,  LAI Bi-Qin ,  WANG Jun-Mei ,  LING Eng-Ang ,  WU Jin-Lang ,  ZENG Yuan-Shan
Material： Journal of Biomedical Materials Research. Part A  (J Biomed Mater Res Pt A)
Volume： 103  Issue： 4  Page： 1533-1545  Publication year： Apr. 2015 
JST Material Number： E0528B  ISSN： 1549-3296  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： neural stem cell ,...
Semi thesaurus term： *gelatin sponge ,...

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JST classification (4)： Basic neurology  (GN01020W) ,  Basic surgery  (GC07012C) ,  Medical materials  (GA05040H) ,  Cell physiology in general  (EF02010S)

Reference (41)：

• Novikova LN, Novikov LN, Kellerth JO. Biopolymers and biodegradable smart implants for tissue regeneration after spinalcord injury. Curr Opin Neurol 2003;16:711-715.
• Yip PK, Malaspina A. Spinal cord trauma and the molecular point of no return. Mol Neurodegener 2012;7:6.
• Joosten EA. Biodegradable biomatrices and bridging the injured spinal cord: the corticospinal tract as a proof of principle. Cell Tissue Res 2012;349:375-395.
• Teng YD, Lavik EB, Qu X, Park KI, Ourednik J, Zurakowski D, Langer R, Snyder EY. Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci USA 2002;99:3024-3029.
• Patist CM, Mulder MB, Gautier SE, Maquet V, Jerome R, Oudega M. Freeze dried poly(D,L-lacticacid) macroporous guidance scaffold impregnated with brain-derived neurotrophic factoring the transected adult rat thoracic spinalcord. Biomaterials 2004;25:1569-1582.

Terms in the title (12)： 遺伝子 ,  修飾 ,  神経幹細胞 ,  ゼラチンスポンジ ,  足場 ,  移植片 ,  脊髄 ,  ラット ,  細胞分化 ,  軸索再生 ,  回復 ,  促進