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J-GLOBAL ID：201502258829102990   Reference number：15A0718074

Clinical evaluation of ezetimibe on bile lithogenicity in humans: Use of transnasal endoscopy for bile sampling

エゼチミブがヒト胆汁の結石形成性へ与える影響を見る臨床評価:胆汁採取に経鼻内視鏡を使用

Author (6)： KISHIKAWA Nobusuke (Dep. of General Internal Medicine, Hiroshima Univ. Hospital, Hiroshima, JPN) ,  KANNO Keishi (Dep. of General Internal Medicine, Hiroshima Univ. Hospital, Hiroshima, JPN) ,  SUGIYAMA Akiko (Dep. of General Internal Medicine, Hiroshima Univ. Hospital, Hiroshima, JPN) ,  YOKOBAYASHI Kenichi (Dep. of General Internal Medicine, Hiroshima Univ. Hospital, Hiroshima, JPN) ,  MIZOOKA Masafumi (Dep. of General Internal Medicine, Hiroshima Univ. Hospital, Hiroshima, JPN) ,  TAZUMA Susumu (Dep. of General Internal Medicine, Hiroshima Univ. Hospital, Hiroshima, JPN)
Material： Hepatology Research  (Hepatol Res)
Volume： 45  Issue： 6  Page： 693-697  Publication year： Jun. 2015 
JST Material Number： W1284A  ISSN： 1386-6346  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： NPC1L1 ,...

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JST classification (1)： Clinical medicine on digestive system in general  (GH01030P)

Substance index (2)： Ezetimibe ,  Cholesterol

Reference (15)：

• Einarsson K, Hellström K, Kallner M. Gallbladder disease in hyperlipoproteinaemia. Lancet 1975; 1: 484-7.
• Tazuma S, Yamashita G, Ochi H et al. Effects of cerivastatin sodium, a new HMG-CoA reductase inhibitor, on biliary lipid metabolism in patients with hypercholesterolemia. Clin Ther 1998; 20: 477-85.
• Carey MC. Pathogenesis of gallstones. Am J Surg 1993; 165: 410-19.
• Wang HH, Portincasa P, de Bari O et al. Prevention of cholesterol gallstones by inhibiting hepatic biosynthesis and intestinal absorption of cholesterol. Eur J Clin Invest 2013; 43: 413-26.
• Altmann SW, Davis HR Jr, Zhu LJ et al. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science 2004; 303: 1201-4.

Terms in the title (7)： エゼチミブ ,  ヒト ,  胆汁 ,  結石 ,  臨床評価 ,  採取 ,  経鼻内視鏡