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J-GLOBAL ID：201502273550907424   Reference number：15A0573215

Identification of molecular target of diallyl trisulfide in leukemic cells

白血病細胞におけるジアリルトリスルフィドの分子標的の同定

Author (10)： SUDA Shun (Nihon Univ., Fujisawa, JPN) ,  WATANABE Kazunari (Nihon Univ., Fujisawa, JPN) ,  TANAKA Yuki (Nihon Univ., Fujisawa, JPN) ,  WATANABE Kazuhiro (Nihon Univ., Fujisawa, JPN) ,  TANAKA Rie (Nihon Univ., Fujisawa, JPN) ,  OGIHARA Jun (Nihon Univ., Fujisawa, JPN) ,  ARIGA Toyohiko (Nihon Univ., Fujisawa, JPN) ,  HOSONO-FUKAO Tomomi (Ochanomizu Univ., Tokyo, JPN) ,  HOSONO Takashi (Nihon Univ., Fujisawa, JPN) ,  SEKI Taiichiro (Nihon Univ., Fujisawa, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 78  Issue： 8  Page： 1415-1417  Publication year： Aug. 2014 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *Leukemia ,...

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JST classification (3)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Proteins and peptides in general  (EB03010N) ,  Aliphatic sulfonic acid,sulfinic acid,sulfenic acid and other compounds  (CF03160J)

Substance index (1)： Diallyl pertrisulfide

Reference (11)：

• Zhou Y, Zhuang W, Hu W, Liu GJ, Wu TX, Wu XT. Consumption of large amounts of Allium vegetables reduces risk for gastric cancer in a meta-analysis. Gastroenterology. 2011;141:80-89.
• Busch C, Jacob C, Anwar A, Burkholz T, Aicha Ba L, Cerella C, Diederich M, Brandt W, Wessjohann L, Montenarh M. Diallylpolysulfides induce growth arrest and apoptosis. Int. J. Oncol. 2010;36:743-749.
• Chen M, Li B, Zhao X, Zuo H, He X, Li Z, Liu X, Chen L. Effect of diallyl trisulfide derivatives on the induction of apoptosis in human prostate cancer PC-3 cells. Mol. Cell. Biochem. 2012;363:75-84.
• Hosono T, Fukao T, Ogihara J, Ito Y, Shiba H, Seki T, Ariga T. Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of β-tubulin. J. Biol. Chem. 2005;280:41487-41493.
• Shankar S, Chen Q, Ganapathy S, Singh KP, Srivastava RK. Diallyl trisulfide increases the effectiveness of TRAIL and inhibits prostate cancer growth in an orthotopic model: molecular mechanisms. Mol. Cancer Ther. 2008;7:2328-2338.

Terms in the title (4)： 白血病細胞 ,  ジアリルトリスルフィド ,  分子標的 ,  同定