Art

J-GLOBAL ID：201502280978444549   Reference number：15A0145301

Prospective Randomized Trial of Treatment for Adult Patients with Intermediate-severity IgA Nephropathy Using Multiple-drug Combined Therapy with or without Mizoribine (MZB)

ミゾリビンあり/なし多剤併用療法を用いて成人中等度IgA腎症治療の前向きランダム化試験

Author (16)： MITARAI Tetsuya (Saitama Medical Univ.) ,  IWANO Masayuki (Univ. Fukui) ,  SHIIKI Hideo (Uda City Hospital) ,  MUSO Eri (Kitano Hospital) ,  YUMURA Wako (International Univ. Health and Welfare Hospital) ,  KIMURA Kenjiro (St. Marianna Univ. School of Medicine) ,  KAWAMURA Tetsuya (Jikei Univ. School of Medicine) ,  HOSOYA Tatsuo (Jikei Univ. School of Medicine) ,  UTSUNOMIYA Yasunori (Hoya Hospital) ,  YORIOKA Noriaki (Hiroshima Kidney Organization) ,  FURUSU Akira (Wajinkai Hospital) ,  MIYAZAKI Masanobu (Miyazaki Medical Clinic) ,  TOMINO Yasuhiko (Juntendo Univ. School of Medicine) ,  HIKI Yoshiyuki (Fujita Health Univ.) ,  MATSUMURA Osamu (Saitama Medical Univ.) ,  ANDO Takashi (Japan Clinical Res. Support Unit)
Material： 新薬と臨床  (Journal of New Remedies & Clinics)
Volume： 64  Issue： 1  Page： 3-15  Publication year： Jan. 10, 2015 
JST Material Number： G0596A  ISSN： 0559-8672  CODEN： SHRIA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *immunosuppressant ,...
Semi thesaurus term： *成人中等度IgA腎症 ,...

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JST classification (3)： Clinical application of immunotherapeutic agents and blood preparations  (GW22020O) ,  Drug therapy(=pharmacotherapy)for urogenital diseases  (GM05020V) ,  Treatment for immunologic diseases,allergic diseases.  (GD04030Y)

Substance index (1)： Mizoribine

Reference (26)：

• Tomino Y, Sakai H. Special study group (IgA nephropathy) on progressive glomerular disease : Clinical guideline for immunoglobulin A (IgA) nephropathy in Japan, second version. Clin Exp NephroL 2003 ; 7(2) : 93-97.
• Donadio JV, Grande JP. IgA nephropathy. N Engl J Med. 2002 ; 347 : 738-743.
• Samuels JA, Strippoli GF, Craig JC, et al. Immunosuppressive agents for treating IgA nephropathy. Cochrane Database Syst Rev. 2003 ; Issue 4 : CD003965.
• Appel GB, Waldman M. The IgA nephropathy treatment dilemma. Kidney Int. 2006 ; 69 : 1939-1944.
• Russo D, Minutolo R, Pisani A, et al. Coadministration of losartan and enalapril exerts additive antiproteinuric effect in IgA nephropathy. Am J Kidney Dis. 2001 ; 38 : 18-25.

Terms in the title (6)： ミゾリビン ,  多剤併用療法 ,  成人 ,  IgA腎症 ,  治療 ,  ランダム化試験