Art
J-GLOBAL ID：201502285595670105   Reference number：15A0262542

Docking model of the nicotinic acetylcholine receptor and nitromethylene neonicotinoid derivatives with a longer chiral substituent and their biological activities

ニコチン性アセチルコリン受容体と長いキラル置換を持つニトロメチレンネオニコチノイド誘導体のドッキングモデルとそれらの生物活性
Author (6)：
NAGAOKA Hikaru

About NAGAOKA Hikaru

(Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN)

About Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN

, 
NISHIWAKI Hisashi

About NISHIWAKI Hisashi

(Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN)

About Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN

, 
KUBO Takuya

About KUBO Takuya

(Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN)

About Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN

, 
AKAMATSU Miki

About AKAMATSU Miki

(Graduate School of Agriculture, Kyoto Univ., Kita-Shirakawa, Sakyo-Ku, Kyoto 606-8502, JPN)

About Graduate School of Agriculture, Kyoto Univ., Kita-Shirakawa, Sakyo-Ku, Kyoto 606-8502, JPN

, 
YAMAUCHI Satoshi

About YAMAUCHI Satoshi

(Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN)

About Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN

, 
SHUTO Yoshihiro

About SHUTO Yoshihiro

(Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN)

About Fac. of Agriculture, Ehime Univ., 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, JPN


Material：
Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)

About Bioorganic & Medicinal Chemistry


Volume： 23  Issue： 4  Page： 759-769  Publication year： Feb. 15, 2015 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*Musca domestica

About Musca domestica

, 
*insecticide

About insecticide

, 
chemical compound

About chemical compound

, 
nicotinic receptor

About nicotinic receptor

, 
affinity

About affinity

, 
quantitative structure-activity relationship

About quantitative structure-activity relationship

, 
steric hindrance

About steric hindrance

, 
displacement(replacement)

About displacement(replacement)

, 
docking

About docking

, 
molecular recognition

About molecular recognition

, 
group(radical)

About group(radical)

, 
binding site

About binding site

, 
hydrophobic

About hydrophobic

, 
stability

About stability

, 
drug metabolism

About drug metabolism

, 
chemical synthesis

About chemical synthesis

, 
amino acid sequence

About amino acid sequence

, 
homology(characteristic)

About homology(characteristic)

, 
nitrogen heterocyclic compound

About nitrogen heterocyclic compound

, 
organochlorine compound

About organochlorine compound

, 
nitramine

About nitramine

, 
neonicotinoid insecticides

About neonicotinoid insecticides


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
Musca domestica

About Musca domestica

, 
キラル置換

About キラル置換

, 
nicotinic acetylcholine receptor

About nicotinic acetylcholine receptor

, 
ニトロメチレンネオニコチノイド誘導体

About ニトロメチレンネオニコチノイド誘導体

, 
neonicotinoid

About neonicotinoid

, 
受容体親和性

About 受容体親和性

, 
metabolic stability

About metabolic stability

, 
substituent

About substituent

, 
molecular docking

About molecular docking


JST classification (3)：
JST classification
Category name(code) classified by JST.
Structure-activity relationship of drugs 
(GV01050B)

About Structure-activity relationship of drugs

,  Pesticides to insect pest 
(FB06020U)

About Pesticides to insect pest

,  Receptors on cell membrane 
(EF04030C)

About Receptors on cell membrane

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Imidacloprid

About Imidacloprid

Terms in the title (7)：
Terms in the title
Keywords automatically extracted from the title.
ニコチン性アセチルコリン受容体

About ニコチン性アセチルコリン受容体

, 
キラル

About キラル

, 
置換

About 置換

, 
誘導体

About 誘導体

, 
ドッキング

About ドッキング

, 
モデル

About モデル

, 
生物活性

About 生物活性


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