Art

J-GLOBAL ID：201502287330691936   Reference number：15A0705838

Organocatalytic asymmetric Michael addition of α-branched aldehydes to vinyl ketones: synthesis of 5-ketoaldehydes possessing a stereo-controlled all-carbon quaternary stereogenic center

有機触媒によるα-分岐アルデヒドのビニルケトン類への不斉Michael付加:立体制御された全炭素不斉四級炭素を有する5-ケトアルデヒド類の合成

Author (5)： YOSHIDA Masanori (National Inst. of Technol., Asahikawa Coll., 2-1-6, Shunko-dai 2-jo, Asahikawa, Hokkaido 071-8142, JPN) ,  UKIGAI Hitoshi (Molecular Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido Univ. ...) ,  SHIBATOMI Kazutaka (Dep. of Environmental and Life Sciences, Toyohashi Univ. of Technol., 1-1 Hibarigaoka, Tempaku-cho, Toyohashi ...) ,  HARA Shoji (Molecular Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido Univ. ...) ,  HARA Shoji (Div. of Chemical Process Engineering, Fac. of Engineering, Hokkaido Univ., Kita 13-jo Nishi 8, Kita-ku, Sapporo ...)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 56  Issue： 25  Page： 3890-3893  Publication year： Jun. 17, 2015 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *aliphatic aldehyde ,  side chain ,  *vinyl compound ,  *aliphatic ketone ,  *catalytic reaction ,  *asymmetric reaction ,  *Michael reaction ,  *stereospecific reaction ,  aromatic compound ,  quaternization ,  amino acid ,  primary amine ,  enantioselective catalysis ,  *asymmetric organocatalysis ,  organic catalyst
Semi thesaurus term： ケトアルデヒド ,  branched chain

JST classification (3)： Addition reaction,elimination reaction  (CF02030M) ,  Aliphatic aldehydes  (CF03180F) ,  Aliphatic ketones  (CF03190Q)

Substance index (14)： 2-Phenylpropanal ,  Phenylalanine ,  Methyl vinyl ketone ,  (R)-2-Phenyl-2-methyl-5-oxohexanal ,  (R)-2-(4-Chlorophenyl)-2-methyl-5-oxohexanal ,  (R)-2-(4-Fluorophenyl)-2-methyl-5-oxohexanal ,  (R)-2-(4-Methylphenyl)-2-methyl-5-oxohexanal ,  (R)-2-(3-Chlorophenyl)-2-methyl-5-oxohexanal ,  (R)-2-(3-Methylphenyl)-2-methyl-5-oxohexanal ,  (R)-2-(2-Naphthyl)-2-methyl-5-oxohexanal ,  (S)-2-(2-Thienyl)-2-methyl-5-oxohexanal ,  (R)-2-Phenyl-2-ethyl-5-oxohexanal ,  (R)-2-Phenyl-2-methyl-5-oxoheptanal ,  (R)-2,5-Diphenyl-2-methyl-5-oxopentanal

Terms in the title (7)： 有機触媒 ,  分岐 ,  アルデヒド ,  Michael付加 ,  立体制御 ,  全炭素 ,  炭素