Art

J-GLOBAL ID：201502291676214988   Reference number：15A0213415

Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis

関節リウマチの日本人患者3267名におけるタクロリムスの安全性と有効性の医薬品市販後調査

Author (6)： TAKEUCHI Tsutomu (Keio Univ. School of Medicine, Tokyo, JPN) ,  KAWAI Shinichi (Toho Univ. School of Medicine, Tokyo, JPN) ,  YAMAMOTO Kazuhiko (Univ. Tokyo Graduate School of Medicine, Tokyo, JPN) ,  HARIGAI Masayoshi (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  ISHIDA Kota (Astellas Pharma Inc, Tokyo, JPN) ,  MIYASAKA Nobuyuki (Tokyo Medical and Dental Univ., Tokyo, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 24  Issue： 1  Page： 8-16  Publication year： 2014 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...

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JST classification (2)： Clinical application of immunotherapeutic agents and blood preparations  (GW22020O) ,  Drug therapy(=pharmacotherapy)for musculoskeletal diseases  (GG05020D)

Substance index (2)： Tacrolimus ,  Methotrexate

Reference (39)：

• Breedveld FC, Dayer JM. Leflunomide: mode of action in the treatment of rheumatoid arthritis. Ann Rheum Dis. 2000;59: 841-9.
• Weyand CM. New insights into the pathogenesis of rheumatoid arthritis. Rheumatology. 2000;39(Suppl 1):3-8.
• Arend WP, Dayer JM. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum. 1995;38:151-60.
• Kino T, Hatanaka H, Miyata S, Inamura N, Nishiyama M, Yajima T, et al. FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiot (Tokyo). 1987;40:1256-65.
• Sakuma S, Kato Y, Nishigaki F, Sasakawa T, Magari K, Miyata S, et al. FK506 potently inhibits T cell activation induced TNF-a and IL-1b production in vitro by human peripheral blood mononuclear cells. Br J Pharmacol. 2000;130:1655-63.

Terms in the title (6)： 関節リウマチ ,  日本人 ,  患者 ,  タクロリムス ,  安全性 ,  医薬品市販後調査