Art

J-GLOBAL ID：201502296027258960   Reference number：15A0468114

Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials

転移性結腸直腸癌におけるextended RAS変異と抗EGFRモノクローナル抗体生存便益 ランダム化比較試験のメタ分析

Author (6)： SORICH M. J. (Flinders Univ., Adelaide) ,  WIESE M. D. (Univ. South Australia, Adelaide) ,  ROWLAND A. (Flinders Univ., Adelaide) ,  KICHENADASSE G. (Flinders Univ., Adelaide) ,  MCKINNON R. A. (Flinders Univ., Adelaide) ,  KARAPETIS C. S. (Flinders Univ., Adelaide)
Material： Annals of Oncology  (Ann Oncol)
Volume： 26  Issue： 1  Page： 13-21  Publication year： Jan. 2015 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： RAS変異 ,...

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JST classification (3)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Reference (26)：

• Dahabreh IJ, Terasawa T, Castaldi PJ, Trikalinos TA. Systematic review: anti-epidermal growth factor receptor treatment effect modification by KRAS mutations. Ann Intern Med 2011 ; 154: 37-49.
• Behl AS, Goddard KAB, Flottemesch TJ et al. Cost-effectiveness analysis of screening for KRAS and BRAF mutations in metastatic colorectal cancer. J Natl Cancer Inst 2012; 104: 1785-1795.
• Douillard JY, Oliner KS, Siena S et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013; 369: 1023-1034.
• Adelstein B-A, Dobbins TA, Harris CA et al. A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer. Eur J Cancer 2011 ; 47: 1343-1354.
• Vale CL, Tierney JF, Fisher D et al. Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis. Cancer Treat Rev 2012; 38: 618-625.

Terms in the title (9)： 転移性結腸直腸癌 ,  Ras ,  変異 ,  EGFR ,  モノクローナル抗体 ,  生存 ,  便益 ,  ランダム化比較試験 ,  メタ分析