Fujihara Kazuyuki

フジハラカズユキ | Fujihara Kazuyuki

Affiliation and department：

Research field (1)： Neuroscience - general

Research keywords (3)： knockout rat , γ-aminobutyric acid , Schizophrenia

Research theme for competitive and other funds (6)：

2021 - 2025 抑制性神経伝達障害に着目した統合失調症の新規治療法開発
2018 - 2023 操作・モデリングから迫る精神病態シナプスパソロジーの多階層理解
2017 - 2022 Pathophysiology of schizophrenia based on analysis of the interaction between the GABAergic system and the neuroimmune system
2015 - 2019 Science of "ego-brain": brain substrates of disability and recovery in psychiatric disorders
2014 - 2017 Specificity of cerebral reactivity in mood disorder and adjustment disorder during transcranial magnetic stimulation

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Papers (26)：

Dongyu Liu, Kazuyuki Fujihara, Yuchio Yanagawa, Hajime Mushiake, Tomokazu Ohshiro. Gad1 knock-out rats exhibit abundant spike-wave discharges in EEG, exacerbated with valproate treatment. Frontiers in Neurology. 2023. 14
Kazuyuki Fujihara. Beyond the γ-aminobutyric acid hypothesis of schizophrenia. Frontiers in Cellular Neuroscience. 2023. 17
Minami Tagawa, Yuichi Takei, Yutaka Kato, Tomohiro Suto, Naruhito Hironaga, Takefumi Ohki, Yumiko Takahashi, Kazuyuki Fujihara, Noriko Sakurai, Koichi Ujita, et al. Disrupted local beta band networks in schizophrenia revealed through graph analysis: A magnetoencephalography study. Psychiatry and Clinical Neurosciences. 2022
Kazuki Komiyama, Keiya Iijima, Reika Kawabata-Iwakawa, Kazuyuki Fujihara, Toshikazu Kakizaki, Yuchio Yanagawa, Yuhei Yoshimoto, Shigeo Miyata. Glioma facilitates the epileptic and tumor-suppressive gene expressions in the surrounding region. Scientific reports. 2022. 12. 1. 6805-6805
Weiru Jiang, Toshikazu Kakizaki, Kazuyuki Fujihara, Shigeo Miyata, Yue Zhang, Takashi Suto, Daiki Kato, Shigeru Saito, Koji Shibasaki, Yasuki Ishizaki, et al. Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022. 36. 2. e22123

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MISC (19)：

Kazuyuki Fujihara, Toshikazu Kakizaki, Weiru Jiang, Shigeo Miyata, Yuchio Yanagawa. Characterization of glutamate decarboxylase 67-kDa and 65-kDa isoforms knockout rats. The Cell. 2021. 53. 7. 47-51
宮田茂雄, 山形弘隆, 松尾幸治, 内田周作, 原田健一郎, 藤原和之, 柳川右千夫, 渡邉義文, 三國雅彦, 中川伸, et al. 中高年齢うつ病患者の白血球に認められる遺伝子発現変化には性差が存在する. 日本薬学会年会要旨集. 2020. 140年会. 26Q-pm076
藤原和之, 藤原和之, 柿崎利和, JIANG Weiru, 宮田茂雄, 宮田茂雄, 須藤貴史, 齋藤繁, 山田一夫, 一谷幸男, et al. GAD67ノックアウトラットの認知機能障害. 日本生物学的精神医学会(Web). 2019. 41st
笠木真人, 茂木智和, 藤原和之, 鈴木雄介, 氏田浩一, 成田耕介, 福田正人. 脳活動のスケールフリーな指標と課題施行中の行動について. 日本ヒト脳機能マッピング学会プログラム・抄録集. 2017. 19th
茂木智和, 笠木真人, 藤原和之, 鈴木雄介, 氏田浩一, NEAR Jamie, 成田耕介, 福田正人. 健常高齢者における後部帯状回GABA濃度とDefault mode networkおよび認知機能の関連性について. 日本ヒト脳機能マッピング学会プログラム・抄録集. 2017. 19th

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Lectures and oral presentations (2)：

精神神経疾患モデルとしてのグルタミン酸脱炭酸酵素GAD67ノックアウトラット
(文部科学省新学術領域研究先端モデル動物支援プラットフォーム成果発表会2020 2021)
Behavioral phenotypes induced by the interaction between GAD67 haploinsuffic iency and neonatal NMDA receptor blockade
(NPBPPP2020 2020)

Education (2)：

Professional career (1)：

Work history (8)：

2022/01 - 現在 Gunma University
2021/04 - 2021/12 群馬大学
2017/04 - 2021/03 Gunma University Molecular Pharmacology and Oncology, Graduate School of Medicine
2014/04 - 2017/03 Gunma University University Hospital, Neuropsychiatry
2010/04 - 2014/03 Gunma University University Hospital, Neuropsychiatry

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Awards (4)：

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