Yuichiro Arima

アリマユウイチロウ | Yuichiro Arima

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://ircms.kumamoto-u.ac.jp/research/yuichiro_arima/

Research field (1)： Cardiology

Research keywords (3)： Ketone body metabolism , Developmental Biology , Cardiovascular Medicine

Research theme for competitive and other funds (10)：

2023 - 2026 ケトン体代謝によるエピゲノム制御作用を介した循環器疾患形成機序の解明
2023 - 2026 生体イメージングと網羅的解析によるミトコンドリア面からみた緑内障とその治療法探索
2022 - 2025 新生児期のケトン体代謝を介した心筋成熟・心内微小環境構築機序の解明
2022 - 2025 心内微小環境に着目したトランスサイレチン型心アミロイドーシス病態解明
2021 - 2023 胎生期の栄養感知シグナルを介した健全な腎臓形成機構の解明

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Papers (196)：

Koichiro Fujisue, Miwa Ito, Yasushi Matsuzawa, Yuichiro Arima, Seiji Takashio, Daisuke Sueta, Satoshi Araki, Shinsuke Hanatani, Kenshi Yamanaga, Masahiro Yamamoto, et al. Open-Label, Single-Center, Single-Arm Study Evaluating the Efficacy and Safety of Elobixibat for Chronic Constipation in Patients With Heart Failure. Circulation Reports. 2024. 6. 3. 55-63
Hiroki Usuku, Eiichiro Yamamoto, Daisuke Sueta, Rumi Shinriki, Fumi Oike, Noriaki Tabata, Masanobu Ishii, Shinsuke Hanatani, Tadashi Hoshiyama, Hisanori Kanazawa, et al. A new staging system using right atrial strain in patients with immunoglobulin light-chain cardiac amyloidosis. ESC heart failure. 2024
Kentaro Oniki, Masatsune Ogura, Erika Matsumoto, Hiroshi Watanabe, Tadashi Imafuku, Yuri Seguchi, Yuichiro Arima, Koichiro Fujisue, Kenshi Yamanaga, Eiichiro Yamamoto, et al. Impaired Cholesterol Efflux Capacity rather than Low HDL-C Reflects Oxidative Stress under Acute Myocardial Infarction. Journal of atherosclerosis and thrombosis. 2024
Masaki Takeyoshi, Wakana Togami, Kei Hiyama, Seiji Takashio, Yuichiro Arima, Kenichi Tsujita, Takeshi Miyamoto. Investigating Gait Speed as the Index of Exercise Tolerance in Heart Failure with Preserved Ejection Fraction. Journal of Modern Rehabilitation. 2024
Wenjuan Ma, Shah Adil Ishtiyaq Ahmad, Michihiro Hashimoto, Ahad Khalilnezhad, Miho Kataoka, Yuichiro Arima, Yosuke Tanaka, Shigeru Yanagi, Terumasa Umemoto, Toshio Suda. MITOL deficiency triggers hematopoietic stem cell apoptosis via ER stress response. The EMBO Journal. 2024. 43. 3. 339-361

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MISC (146)：

西垣愛奈, 成田勇樹, 有馬勇一郎, 辻田賢一, 城野博史, 齋藤秀之. 硫酸転移酵素Sult1a1欠損マウスを用いた慢性腎臓病の心血管疾患発症に対するインドキシル硫酸の寄与解明. 日本腎臓学会誌(Web). 2022. 64. 3
西垣愛奈, 山田敏寛, 成田勇樹, 有馬勇一郎, 辻田賢一, 城野博史, 齋藤秀之, 山田敏寛, 成田勇樹, 有馬勇一郎, et al. 硫酸転移酵素Sult1a1欠損マウスを用いた心腎連関に対するインドキシル硫酸の寄与解明. 日本薬理学雑誌. 2022. 157. Supplement
戸田真志, 右田雅裕, 有馬勇一郎. 3-Dimensional Analysis for Microscopic Images of Heart and Its Application. 電気学会電子・情報・システム部門大会(Web). 2021. 2021
有馬勇一郎, 有馬勇一郎, 辻田賢一, 辻田賢一. Cardiac regulation by ketone bodies. 医学のあゆみ. 2021. 276. 12
有馬勇一郎, 有馬勇一郎, 辻田賢一. The concept of DOHaD hypothesis in the cardiovascular field. 日本小児科学会雑誌. 2021. 125. 2

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Lectures and oral presentations (13)：

心血管代謝におけるケトン体代謝の意義
(第27日本血管生物医学会学術集会(血管代謝週間2019) 2019)
冠動脈-冠静脈洞同時採血による心筋代謝解析
(第127回日本循環器学会九州地方会 2019)
心臓におけるケトン体合成能の意義
(第67回日本心臓病学会学術集会 2019)
新生児期のケトン体合成は翻訳後修飾を介してミトコンドリア機能を保護する
(第8回日本DOHaD学会学術集会 2019)
Epigenetic Modification by Perinatal Environmental Stress and its Lifelong Effects to Cardiovascular Diseases
(第83回日本循環器学会学術集会 2019)

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Education (2)：

2009 - 2013 The University of Tokyo Graduate School of Medicine Molecular Cell Biology
1998 - 2004 Kumamoto University

Professional career (1)：

MD, PhD (The University of Tokyo)

Work history (10)：

2021/04 - 現在 Kumamoto University International Research Center for Medical Sciences Developmental Cardiology, Associate professor
2019/04 - 2021/03 Kumamoto University International Research Center for Medical Science Principal investigator
2018/04 - 2021/03 熊本大学生命科学研究部循環器内科助教
2017/04 - 2018/03 Kumamoto University University Hospital
2016/04 - 2017/03 Kumamoto University University Hospital

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Committee career (1)：

- 現在日本血管生物医学会評議員

Awards (9)：

2022/09 - Society for Hypertension Related Disease Model Research Nagai Award Elucidation of pathology of lifestyle-related diseases focusing on ketone body metabolism
2021/12 - The Japan Research Foundation for Healthy Aging Young Investigator Imura Award Ketone body metabolism on development, aging and disease
2021/03 - The Society of Cardiovascular Endocrinology and Metabolism Jokichi Takamine Young Investigator Award Cardiovascular regulation by ketone body metabolism
2018/09 - Japanese College of Cardiology Young Investigator Awards
2018/07 - 泰江賞

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Association Membership(s) (7)：

THE JAPANESE BIOCHEMICAL SOCIETY , 日本DOHaD学会 , 日本血管生物医学会 , 日本心血管内分泌代謝学会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , The Japanese Circulation Society , THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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