Yuichiro Arima

アリマユウイチロウ | Yuichiro Arima

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://ircms.kumamoto-u.ac.jp/research/yuichiro_arima/

Research field (1)： Cardiology

Research keywords (4)： Anatomy , Developmental Biology , Ketone body metabolism , Cardiovascular Medicine

Research theme for competitive and other funds (14)：

2026 - 2032 空腹代謝の理解に基づく生活習慣病予防戦略の開発
2024 - 2028 Unraveling the Brain Structure, Function, and Epigenomic Vulnerability of Psychological Resilience.
2023 - 2026 ケトン体代謝によるエピゲノム制御作用を介した循環器疾患形成機序の解明
2023 - 2026 生体イメージングと網羅的解析によるミトコンドリア面からみた緑内障とその治療法探索
2022 - 2025 新生児期のケトン体代謝を介した心筋成熟・心内微小環境構築機序の解明

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Papers (197)：

Shoichiro Kuroda, Shintaro Funasaki, Hidekazu Nishizawa, Laura S. Schmidt, Ryoma Kurahashi, Takaaki Ito, Yuichiro Arima, Miwa Tanaka, Atsuya Kitada, Amy M. James, et al. The Cyclin C-CDK8/19 Mediator kinase module controls PRCC-TFE3 driven senescence in renal epithelium and tumorigenesis in TFE3-RCC. NEOPLASIA. 2026. 75
Satoru Suzuki, Kenshi Yamanaga, Masanobu Ishii, Erika Matsumoto, Naoto Kuyama, Kyoko Hirakawa, Noriaki Tabata, Tomonori Akasaka, Koichiro Fujisue, Shinsuke Hanatani, et al. The impact of mildly elevated HbA1c level, and low levels of high-density lipoprotein cholesterol and hemoglobin on microvascular angina. Heart and vessels. 2026
Hiroki Usuku, Eiichiro Yamamoto, Kanako Imamura, Ryudai Higashi, Atsushi Nozuhara, Fumi Oike, Naoto Kuyama, Masanobu Ishii, Shinsuke Hanatani, Tadashi Hoshiyama, et al. Usefulness of Regional Longitudinal Strain to Identify Transthyretin Amyloid Cardiomyopathy. Circulation reports. 2026. 8. 3. 495-497
Kei Morikawa, Yuichiro Arima, Takumi Nagakura, Yuqing Xu, Akira Fujiyama, Miho Kataoka, Shinsuke Hanatani, Yasushi Matsuzawa, Yasuhiro Izumiya, Eiichiro Yamamoto, et al. Nonsteroidal mineralocorticoid receptor antagonist finerenone ameliorates cardiac hypertrophy with increasing glucocorticoid signaling sensitivity. Biochemical and biophysical research communications. 2026. 802. 153332-153332
Rieko Asai, Yuichiro Arima. Translating Cardiac Development Insights to Non-Invasive Prenatal Intervention - Maternal Administration for Neural Crest-Related Congenital Heart Disease. Circulation journal : official journal of the Japanese Circulation Society. 2026

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MISC (156)：

Aina Sugiura, Kaito Makise, Yuki Narita, Yutaka Kakizoe, Yuichiro Izumi, Takashige Kuwabara, Yuichiro Arima, Kenichi Tsujita, Hirofumi Jono, Hideyuki Saito. Effects of Suppressed Indoxyl Sulfate Production on Kidney Injury-Associated Cardiac Pathogenesis in Sult1a1-Deficient Mice. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2024. 35. 10
杉浦愛奈, 牧瀬海豊, 成田勇樹, 有馬勇一郎, 辻田賢一, 城野博史, 齋藤秀之. 硫酸転移酵素Sult1a1欠損マウスにおける腎障害併発心不全に及ぼすインドキシル硫酸産生抑制の影響. 日本腎臓学会誌(Web). 2024. 66. 4
金子昌太郎, 有馬勇一郎, 右田雅裕, 戸田真志. 3次元形態情報と生理学的特徴を用いた心筋組織画像における細胞分類. 動的画像処理実利用化ワークショップ講演論文集(CD-ROM). 2024. 2024
荒木貴光, 有馬勇一郎, 右田雅裕, 戸田真志. Attribute Classification and Validation of Cell Nuclei for Three-dimentional Imaging of Myocardial Tissue of Mice-The Format of Technical Report (Subtitle)-. 情報処理学会研究報告(Web). 2024. 2024. AVM-125
金子昌太郎, 有馬勇一郎, 右田雅裕, 戸田真志. マウスの心筋組織画像における生理学的特徴に基づいた細胞分類手法. ViEWビジョン技術の実利用ワークショップ講演論文集(CD-ROM). 2023. 2023

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Lectures and oral presentations (13)：

心血管代謝におけるケトン体代謝の意義
(第27日本血管生物医学会学術集会(血管代謝週間2019) 2019)
冠動脈-冠静脈洞同時採血による心筋代謝解析
(第127回日本循環器学会九州地方会 2019)
心臓におけるケトン体合成能の意義
(第67回日本心臓病学会学術集会 2019)
新生児期のケトン体合成は翻訳後修飾を介してミトコンドリア機能を保護する
(第8回日本DOHaD学会学術集会 2019)
Epigenetic Modification by Perinatal Environmental Stress and its Lifelong Effects to Cardiovascular Diseases
(第83回日本循環器学会学術集会 2019)

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Education (2)：

2009 - 2013 The University of Tokyo Graduate School of Medicine Molecular Cell Biology
1998 - 2004 Kumamoto University

Professional career (1)：

MD, PhD (The University of Tokyo)

Work history (11)：

2025/08 - 現在 Kumamoto University Department of Anatomy, Faculty of Life Sciences Associate Professor
2021/04 - 2025/07 Kumamoto University International Research Center for Medical Sciences Developmental Cardiology, Associate professor
2019/04 - 2021/03 Kumamoto University International Research Center for Medical Science Principal investigator
2018/04 - 2021/03 熊本大学生命科学研究部循環器内科助教
2017/04 - 2018/03 Kumamoto University University Hospital

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Committee career (1)：

- 現在日本血管生物医学会評議員

Awards (9)：

2022/09 - Society for Hypertension Related Disease Model Research Nagai Award Elucidation of pathology of lifestyle-related diseases focusing on ketone body metabolism
2021/12 - The Japan Research Foundation for Healthy Aging Young Investigator Imura Award Ketone body metabolism on development, aging and disease
2021/03 - The Society of Cardiovascular Endocrinology and Metabolism Jokichi Takamine Young Investigator Award Cardiovascular regulation by ketone body metabolism
2018/09 - Japanese College of Cardiology Young Investigator Awards
2018/07 - 泰江賞

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Association Membership(s) (7)：

THE JAPANESE BIOCHEMICAL SOCIETY , 日本DOHaD学会 , 日本血管生物医学会 , 日本心血管内分泌代謝学会 , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , The Japanese Circulation Society , THE JAPANESE SOCIETY OF INTERNAL MEDICINE

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