Rchr
J-GLOBAL ID：201601004343940512   Update date: Jan. 30, 2024

KOTA KASAHARA

カサハラ コウタ | KOTA KASAHARA
Homepage URL  (1)： http://ktkshr.net
Research field  (1)： Biophysics
Research keywords  (1)： Bioinformatics, Pattern Recognition, Molecular Simulation, Molecular Dynamics, Protein, Intrinsically Disordered, Ion Channel, Rational Drug Design, Post Translational Modification, Protein Design
Research theme for competitive and other funds  (4)：
  • 2021 - 2024 膜蛋白質 GPCR と薬剤化合物ボセンタンの結合自由エネルギー地形
  • 2020 - 2022 Study of the phosphorylation latch mechanism for the transcriptional regulation via intrinsically disordered regions
  • 2016 - 2019 Computational design of novel proteins with weak interactions
  • 2012 - 2017 Elucidation of information-processing mechanisms during transcription cycle using computational and information sciences
Papers (44)：
  • Shin-Ichiro Yamaguchi, Qilin Xie, Fumiya Ito, Kazuki Terao, Yoshinobu Kato, Miki Kuroiwa, Satoshi Omori, Hideo Taniura, Kengo Kinoshita, Takuya Takahashi, et al. Carbon nanotube recognition by human Siglec-14 provokes inflammation. Nature nanotechnology. 2023
  • Toru Sengoku, Masaaki Shiina, Kae Suzuki, Keisuke Hamada, Ko Sato, Akiko Uchiyama, Shunsuke Kobayashi, Asako Oguni, Hayato Itaya, Kota Kasahara, et al. Structural basis of transcription regulation by CNC family transcription factor, Nrf2. Nucleic Acids Research. 2022. 50. 21. 12543-12557
  • Tomomi Ukawa, Fumihiko Banno, Toshiki Ishikawa, Kota Kasahara, Yuuta Nishina, Rika Inoue, Keigo Tsujii, Masatoshi Yamaguchi, Takuya Takahashi, Yoichiro Fukao, et al. Sphingolipids with 2-hydroxy fatty acids aid in plasma membrane nanodomain organization and oxidative burst. Plant Physiology. 2022. 189. 2. 839-857
  • Shun Sakuraba, Qilin Xie, Kota Kasahara, Junichi Iwakiri, Hidetoshi Kono. Extended ensemble simulations of a SARS-CoV-2 nsp1-5’-UTR complex. PLOS Computational Biology. 2022. 18. 1. e1009804-e1009804
  • Tomonori Hayami, Narutoshi Kamiya, Kota Kasahara, Takeshi Kawabata, Jun-ichi Kurita, Yoshifumi Fukunishi, Yoshifumi Nishimura, Haruki Nakamura, Junichi Higo. Difference of binding modes among three ligands to a receptor mSin3B corresponding to their inhibitory activities. Scientific Reports. 2021. 11. 1
ｍore...
MISC (2)：
  • Ikuo Fukuda, Narutoshi Kamiya, Han Wang, Kota Kasahara, Haruki Nakamura. Development and application of novel non-Ewald methods for calculating electrostatic interactions in molecular simulations. PROTEIN SCIENCE. 2015. 24. 290-290
  • Matsuyuki Shirota, Susumu Chiba, Kota Kasahara, Kengo Kinoshita. Exploring the proton permeation pathway by using homology modeling and molecular dynamics simulation of the Hv1 proton channel. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S55-S55
Books (3)：
  • in silico創薬におけるスクリーニングの高速化・高精度化技術
    技術情報協会 2018 ISBN:4861046882
  • 見て分かる構造生命科学
    化学同人 2014
  • 岩波講座 計算科学4 計算と生命
    岩波書店 2012
Lectures and oral presentations  (39)：
  • N-gram analysis of amino acid sequences toward elucidating mechanisms of protein-protein interactions
    (第16回日本蛋白質科学会年会 2018)
  • Study on helix-coil transition stability of the termini of poly-glutamic acid using molecular dynamics method
    (第55回日本生物物理学会年会 2017)
  • The dominant structure of polyglutamic acids under an acidic conditions analyzed by replica-exchange molecular dynamics simulations.
    (第55回日本生物物理学会年会 2017)
  • A new prediction method for complex structures of protein and small molecule with machine learning.
    (第55回日本生物物理学会年会 2017)
  • Investigation of appropriate conditions for enhancing sampling efficiency of multi-canonical molecular dynamics.
    (第55回日本生物物理学会年会 2017)
ｍore...
Education (4)：
  • - 2010 The University of Tokyo Graduate School of Frontier Sciences Department of Computational Biology
  • - 2007 Tohoku University Graduate School of Engineering Department of Applied Chemistry
  • - 2005 Tohoku University School of Engineering Department of Molecular and Chemical Engineering
  • - 2003 Nagaoka College, National Institute of Technology Department of Material Engineering
Professional career (1)：
  • Ph.D. (The University of Tokyo)
Work history (3)：
  • 2013/01/01 - 2016/03/31 Postdoctoral Fellow, Institute for Protein Research, Osaka University
  • 2010/10/01 - 2012/12/31 Postdoctoral Fellow, Graduate School of Information Sciences, Tohoku University
  • 2008/04/01 - 2009/03/31 Research Fellow of the Japan Society for the Promotion of Science
Association Membership(s) (3)：
Japanese Society for Bioinformatics ,  Biophysical Society of Japan ,  Protein Science Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM