- 2020 - 2023 新規治療薬開発を目指した腫瘍微小環境におけるPD-L1発現の意義と機序解明
- 2020 - 2023 膵癌におけるPD-L1/PD-1クロストークが癌細胞に与える影響
- 2018 - 2021 The mechanism of promoting liver metastasis caused by CXCL 12 and fundamental research for innovative therapeutic development in intrahepatic cholangiocarcinoma
- 2018 - 2021 Signal crosstalk between TGF-beta and Hippo-pathway in pancreatic
- 2018 - 2021 Analysis of the interaction between pancreatic stromal cells and adenocarcinoma via complement component 5a receptor
- 2016 - 2019 The role of tumor-associated neutrophil in the progression of hepatocellular carcinoma.
- 2018 - 根治的肝切除又はアブレーション後の再発高リスク肝細胞がん患者を対象に術後補助療法としてのニボルマブとプラセボを比較する無作為化二重盲検第III相試験
- 2015 - 2018 Drug screening for cholangiocarcinoma targeting the epigenetical mechanism of cancer progression
- 2015 - 2018 Analysis of tumor-stromal interaction via complement C5a receptor in cancer microenvironment
- 2015 - 2017 Therapeutic implication for cancer-associated fibroblasts (CAF) in cholangiocarcinoma
- 2014 - 2017 Clinical implication of Farnesoid-X-receptor agonist in liver regeneration after hepatectomy
- 2012 - 2015 Characterization of circulating tumor cells and its application of the treatment selection for hepatocellular carcinoma
- 2012 - 2015 The role of polycomb protein expression and application for epigenetic therapy in cholangiocarcinoma.
- 2011 - 2013 The isolation and characterization of cancer associated fibroblasts for clinical therapeutic application.
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