Rchr
J-GLOBAL ID：201601006489043680
Update date: May. 31, 2024
Nishinaka-Arai Yoko
ニシナカ ヨウコ | Nishinaka-Arai Yoko
Affiliation and department：
Research field (5)：
Pathobiochemistry
, Cell biology
, Fetal medicine/Pediatrics
, Hematology and oncology
, Infectious disease
Research keywords (3)：
Transient abnormal myelopoiesis
, Neutrophils
, Reactive oxygen soecies
Research theme for competitive and other funds (4)：
- 2024 - 2027 一過性骨髄異常増殖症モデルを用いたがんのクローン進化のメカニズム解明
- 2022 - 2024 一過性骨髄異常増殖症の発症過程における短型GATA1タンパクの機能解析
- 2019 - 2022 Exploring the mechanism of mutation acquisition to induce tumorigenesis using Down syndrome associated leukemia model
- 2011 - 2012 一重項酸素の制御による細胞傷害の緩和
Papers (25)：
-
Hiromitsu Toshikawa, Akihiro Ikenaka, Li Li, Yoko Nishinaka-Arai, Akira Niwa, Akira Ashida, Yasuhiro Kazuki, Tatsutoshi Nakahata, Hiroshi Tamai, David W Russell, et al. N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21. Scientific reports. 2021. 11. 1. 17377-17377
-
Mina Noura, Ken Morita, Hiroki Kiyose, Yukiko Okuno, Hidemasa Matsuo, Asami Koyama, Yoko Nishinaka-Arai, Yasuhiko Kamikubo, Souichi Adachi. Albendazole induces the terminal differentiation of acute myeloid leukaemia cells to monocytes by stimulating the Krüppel-like factor 4-dihydropyrimidinase-like 2A (KLF4-DPYSL2A) axis. British journal of haematology. 2021. 194. 3. 598-603
-
Shiori Matsuo, Yoko Nishinaka-Arai, Yasuhiro Kazuki, Mitsuo Oshimura, Tatsutoshi Nakahata, Akira Niwa, Megumu K Saito. Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification. PloS one. 2021. 16. 3. e0247595
-
Kana Nakatani, Hidemasa Matsuo, Yutarou Harata, Moe Higashitani, Asami Koyama, Mina Noura, Yoko Nishinaka-Arai, Yasuhiko Kamikubo, Souichi Adachi. Inhibition of CDK4/6 and autophagy synergistically induces apoptosis in t(8;21) acute myeloid leukemia cells. International journal of hematology. 2021. 113. 2. 243-253
-
Yoko Nishinaka-Arai, Akira Niwa, Shiori Matsuo, Yasuhiro Kazuki, Yuwna Yakura, Takehiko Hiroma, Tsutomu Toki, Tetsushi Sakuma, Takashi Yamamoto, Etsuro Ito, et al. Down syndrome-related transient abnormal myelopoiesis is attributed to a specific erythro-megakaryocytic subpopulation with GATA1 mutation. Haematologica. 2021. 106. 2. 635-640
ｍore...
MISC (16)：
-
Kana Nakatani, Hidemasa Matsuo, Yutarou Harata, Moe Higashitani, Asami Koyama, Mina Noura, Yoko Nishinaka-Arai, Yasuhiko Kamikubo, Souichi Adachi. Autophagy Inhibition Enhances CDK4/6 Inhibitor-Induced Apoptosis in t(8;21) Acute Myeloid Leukemia Cells. BLOOD. 2020. 136
-
Hidemasa Matsuo, Naomi Nakamura, Daisuke Tomizawa, Akiko M. Saito, Nobutaka Kiyokawa, Keizo Horibe, Yoko Nishinaka-Arai, Mayu Tokumasu, Hiroshi Itoh, Yasuhiko Kamikubo, et al. Prognostic Significance of CXCR4 Overexpression in Pediatric Acute Myeloid Leukemia with Low-Risk: A Report from the Japanese Pediatric Leukemia/Lymphoma Study Group. BLOOD. 2015. 126. 23
-
MATSUO Hidemasa, MATSUO Hidemasa, NAKAMURA Naomi, TOMIZAWA Daisuke, WATANABE Tomoyuki, MORIYA SAITO Akiko, FUJIMOTO Jun-ichiro, HORIBE Keizo, NISHINAKA Yoko, TOKUMASU Mayu, et al. Prognostic significance of CXCR4 overexpression in pediatric AML: the JPLSG AML-05 study. 臨床血液. 2015. 56. 9. 1453
-
丹羽明, 伊藤潤, 西中瑶子, 鈴木直也, 斎藤潤, 中畑龍俊. ヒト多能牲幹細胞を用いた,完全無血清条件下での成体型ヘモグロビン産生赤芽球への効率的分化誘導法の開発. 再生医療. 2015. 14. 305
-
西中瑶子, 山本美月, 足立壯一, 荒井俊之. 神経細胞内で発生させた一重項酸素により誘導される細胞死の検討. 日本酸化ストレス学会学術集会プログラム・抄録集. 2014. 67th
ｍore...
Patents (2)：
Education (4)：
- 2010 - 2013 京都大学大学院 医学研究科 人間健康科学系専攻 博士課程
- 2008 - 2010 京都大学大学院 医学研究科 人間健康科学系専攻 修士課程
- 2004 - 2008 Kyoto University Faculty of Medicine School of Human Health Sciences Department of Laboratory Science
- 2001 - 2004 大阪教育大学教育学部附属高等学校天王寺校舎
Professional career (1)：
Work history (6)：
Association Membership(s) (3)：
American Society of Hematology
, 日本酸化ストレス学会
, 日本血液学会
